Improving Diagnostic Standards in Dysphagia

CompletedOBSERVATIONAL
Enrollment

46

Participants

Timeline

Start Date

April 27, 2021

Primary Completion Date

September 23, 2023

Study Completion Date

September 23, 2023

Conditions
Dysphagia
Interventions
PROCEDURE

Fiberoptic Endoscopic Evaluation of Swallowing

This procedure involves inserting a flexible laryngoscope that contains a light source and video camera on the end through the open passage of the nose towards the back of the throat in order to visualize the swallowing mechanism.

PROCEDURE

Videofluoroscopic Swallowing Study

Videofluoroscopic swallowing study will be performed to measure oropharyngeal swallowing. This is like a moving x-ray of the swallow.

PROCEDURE

Voluntary Peak Cough Flow Testing

Voluntary peak cough flow testing will be performed to determine the peak expiratory flow (PEF) and volume of air expelled (FEV1) during voluntary coughing.

PROCEDURE

Iowa Oral Performance Instrument

The Iowa Oral Performance Instrument (IOPI) is a device that measures the peak pressure performance of lingual strength and endurance via the action of a bulb placed on the hard palate.

PROCEDURE

Capsaicin Challenge

"A capsaicin challenge with three randomized blocks of 0, 50, 100, 200, and 500 μM capsaicin. The capsaicin will be dissolved in a vehicle solution consisting of 80% physiological saline, and 20% ethanol. Participants will be given the instruction cough if you need to prior to capsaicin delivery.The solution will be administered automatically upon detection of an inspired breath and there will be a minimum of one minute between each trial. This is to test the reflexive cough testing for upper airway sensitivity and motor thresholds."

PROCEDURE

Pulmonary Function Testing

Pulmonary Function testing will be performed using conventional methods and will include the following outcomes: forced vital capacity (FVC), maximum inspiratory pressure (MIP), and maximum expiratory pressure (MEP) expressed as a percentage of predicted values.

OTHER

Voicing Tasks

Voicing tasks will be completed to assess vocal ability.

Trial Locations (1)

32610

University of Florida Health, Gainesville

All Listed Sponsors
lead

University of Florida

OTHER