The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis

NACompletedINTERVENTIONAL
Enrollment

9

Participants

Timeline

Start Date

January 1, 2017

Primary Completion Date

January 9, 2018

Study Completion Date

January 22, 2018

Conditions
Hepatic EncephalopathyLiver CirrhosisSleep Disturbance
Interventions
DIETARY_SUPPLEMENT

Amino Acid Challenge (AAC)

The AAC contains 54 g banana flavoured amino acid mixture added 200-300 mL of water. The AAC simulates the composition of haemoglobin in approximately 400 mL of blood.

Trial Locations (1)

2100

Department of gastroenterology and hepatology, Rigshospitalet, Copenhagen

All Listed Sponsors
lead

Rigshospitalet, Denmark

OTHER

NCT04771104 - The Effect of Induced Hyperammonaemia on Sleep and Melanopsin-mediated Pupillary Light Response in Patients With Liver Cirrhosis | Biotech Hunter | Biotech Hunter