Pre-oxygenation With Facemask Oxygen vs High-flow Nasal Oxygen vs High-flow Nasal Oxygen Plus Mouthpiece Oxygen

NACompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

August 1, 2020

Primary Completion Date

January 13, 2021

Study Completion Date

January 13, 2021

Conditions
ApneaRespiration; ArrestAnesthesia
Interventions
OTHER

Pre-oxygenation

"Induction of anaesthesia after 2mins 45 seconds of pre-oxygenation with 1-1.5mcg/kg remifentanil plus 2-3mg/kg propofol. Propofol (10mg/kg/hr) and remifentanil (0.15mcg/kg/min) infusions commenced until study conclusion.~Positive pressure ventilation commenced at Sp02 92%. Failure to intubate the patient during the first minute of apnoea results in withdrawal from the study.~Blood samples obtained from an arterial catheter immediately prior to commencing pre-oxygenation, after 90 and 180 seconds of pre-oxygenation, after one minute of apnoea, and every two minutes during the apnoeic period."

Trial Locations (1)

Unknown

University Hospital Galway, Galway

All Listed Sponsors
lead

University College Hospital Galway

OTHER

NCT04767867 - Pre-oxygenation With Facemask Oxygen vs High-flow Nasal Oxygen vs High-flow Nasal Oxygen Plus Mouthpiece Oxygen | Biotech Hunter | Biotech Hunter