Regenerative Potential of Advanced Platelet Rich Fibrin and Bioactive Glass (Perioglas®).

PHASE4CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

December 1, 2020

Primary Completion Date

February 18, 2022

Study Completion Date

March 4, 2022

Conditions
Chronic PeriodontitisBone LossIntrabony Periodontal Defect
Interventions
PROCEDURE

open flap debridement and filled with A-PRF ( Advanced platelet rich fibrin)

After phase 1 therapy, surgical procedure would be carried out in the selected patients under aseptic conditions. Full thickness mucoperiosteal Kirkland flap would be raised on both buccal and lingual sides using periosteal elevator. Pocket lining epithelium would be removed and a thorough debridement and root planing would be done in the intrabony defect by using Gracey curettes and universal curettes. After placement of A-PRF in bony defect site the mucoperiosteal flaps would be sutured for complete soft tissue closure.

PROCEDURE

open flap debridement and filled with Bioactive glass (Perioglas®)

After phase 1 therapy, surgical procedure would be carried out in the selected patients under aseptic conditions. Full thickness mucoperiosteal Kirkland flap would be raised on both buccal and lingual sides using periosteal elevator. Pocket lining epithelium would be removed and a thorough debridement and root planing would be done in the intrabony defect by using Gracey curettes and universal curettes. After placement of perioglas in bony defect site the mucoperiosteal flaps would be sutured for complete soft tissue closure.

DRUG

open flap debridement and filled Bioactive glass (Perioglas®) and A-PRF

After phase 1 therapy, surgical procedure would be carried out in the selected patients under aseptic conditions. Full thickness mucoperiosteal Kirkland flap would be raised on both buccal and lingual sides using periosteal elevator. Pocket lining epithelium would be removed and a thorough debridement and root planing would be done in the intrabony defect by using Gracey curettes and universal curettes. After placement of perioglas with A-PRF in bony defect site the mucoperiosteal flaps would be sutured for complete soft tissue closure.

Trial Locations (1)

133207

Department of Periodontology, M.M. College of Dental Sciences and Research., Ambāla

All Listed Sponsors
lead

Maharishi Markendeswar University (Deemed to be University)

OTHER

NCT04767243 - Regenerative Potential of Advanced Platelet Rich Fibrin and Bioactive Glass (Perioglas®). | Biotech Hunter | Biotech Hunter