Arginine Supplementation to Improve Cardiovascular and Endothelial Function After NSAID Treatment

PHASE4CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

June 10, 2021

Primary Completion Date

January 24, 2022

Study Completion Date

January 24, 2022

Conditions
Healthy
Interventions
DRUG

Celecoxib

Two 200 mg capsules per day (400 mg/day) for 7 days

OTHER

Placebo

2 capsules/day for 7 days

OTHER

L-arginine + placebo

L-arginine = Five capsules of 2 mg per day (10 mg/day) for 7 days Placebo = 2 capsules/day for 7 days

OTHER

L-arginine + celecoxib

L-arginine = Five capsules of 2 mg per day (10 mg/day) Celecoxib = Two 200 mg capsules per day (400 mg/day) for 7 days

Trial Locations (1)

w12 0HS

Imperial College Clinical Research Facility, London

All Listed Sponsors
lead

Imperial College London

OTHER