WashIn /WashOut Procedure To Prevent Agitation During Recovery After Inhalational Anesthesia With Sevoflurane

NAActive, not recruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

March 10, 2021

Primary Completion Date

February 25, 2025

Study Completion Date

February 25, 2026

Conditions
Agitation, EmergencePostoperative DeliriumPostoperative Cognitive Dysfunction
Interventions
PROCEDURE

WashIn /WashOut

"According Wash In / WashOut procedure in study group we stop the supply of sevoflurane to the first signs of awakening and record the level of sevoflurane , then we resume the supply of sevoflurane to the end-tidal concentration of 1 MAC maintain the anesthesia for 5 min and stop the supply of sevoflurane to the first signs of awakening again, then we resume the supply of sevoflurane to the end-tidal concentration of 1 MAC maintain the anesthesia for 5 min and finally ( the third time) stop supplying sevoflurane and extubate patient after recovery of muscle tone, spontaneous breathing and consciousness."

Trial Locations (3)

111123

Moscow Scientific Clinical Center, Moscow

129110

Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy, Moscow

Unknown

Clinical hospital №1 of the I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow

All Listed Sponsors
lead

I.M. Sechenov First Moscow State Medical University

OTHER