Hypertension and Retinal Microvascular Dysfunction

NACompletedINTERVENTIONAL
Enrollment

85

Participants

Timeline

Start Date

February 12, 2021

Primary Completion Date

May 1, 2022

Study Completion Date

May 20, 2022

Conditions
Hypertension
Interventions
BEHAVIORAL

HIIT exercise intervention

The exercise intervention will be eight weeks of high-intensity interval training (HIIT) started by one warm-up week with an intensity of 75% maximum heart rate (HRmax). In the following seven weeks, the participants will perform a HIIT based on the following protocol and with a total duration of 45 minutes per session: warm-up for 10 minutes at 60-70% HRmax followed by a high-intensity interval consisting of 4x4 minutes at 80-90% HRmax with 3 minutes of active recovery at 60-70% HRmax and a 10 minutes cool-down at 60-70% HRmax. HR will be monitored during training by Polar® H7 heart rate sensors combined with Polar® M400 watches.

BEHAVIORAL

Physical activity recommendations

The control group will get physical activity recommendations based on actual guidelines from the European Association of Preventive Cardiology.

Trial Locations (1)

4052

Department of Sports, Exercise and Health, Basel

All Listed Sponsors
lead

University of Basel

OTHER

NCT04763005 - Hypertension and Retinal Microvascular Dysfunction | Biotech Hunter | Biotech Hunter