NCT04762134View on ClinicalTrials.gov

Doxycycline Intervention for Bacterial STI ChemoprOphylaxis (DISCO)

NARecruitingINTERVENTIONAL
Enrollment

560

Participants

Timeline

Start Date

June 2, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

June 30, 2027

Conditions
Bacterial Sexually Transmitted Diseases
Interventions
DRUG

Doxycycline Hyclate

STI PrEP arm: doxycycline capsules 100mg orally daily for 12 months STI PEP arm: doxycycline 200mg orally once within 24-72 hours following each sexual encounter deemed at risk (i.e. condomless anal or oral sex), to a maximum of six pills (i.e. 600 mg total) per week

Trial Locations (6)

Unknown

RECRUITING

Sheldon Chumir Centre, Calgary

NOT_YET_RECRUITING

St. Joseph's Healthcare Hamilton, Hamilton

NOT_YET_RECRUITING

The Ottawa Hospital, Ottawa

RECRUITING

St. Michael's Hospital, Toronto

RECRUITING

McGill University Health Centre, Montreal

V5Z4R4

RECRUITING

BC Centre for Disease Control, Vancouver

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

lead

Jonathan Troy Grennan

OTHER_GOV