COVID19 SARS Vaccinations: Systemic Allergic Reactions to SARS-CoV-2 Vaccinations

PHASE2CompletedINTERVENTIONAL
Enrollment

746

Participants

Timeline

Start Date

April 7, 2021

Primary Completion Date

April 20, 2022

Study Completion Date

April 27, 2022

Conditions
SARS-CoV InfectionCOVID-19Allergic ReactionMast Cell Disorder
Interventions
BIOLOGICAL

Moderna COVID-19 Vaccine

Intramuscular injection

BIOLOGICAL

Pfizer-BioNTech COVID-19 Vaccine

Intramuscular injection

BIOLOGICAL

Placebo

Intramuscular injection

Trial Locations (29)

10029

Mount Sinai Hospital, Department of Medicine, Division of Clinical Immunology, New York

10032

Columbia University Irving Medical Center, New York

14607

Rochester Regional Health, Rochester

17033

Penn State Health Allergy, Milton S. Hershey Medical Center, Hershey

21224

Johns Hopkins Bayview Medical Center, Baltimore

22908

University of Virginia Health System: Department of Medicine, Division of Allergy and Immunology, Charlottesville

23298

Virginia Commonwealth University, Department of Internal Medicine, Division of Rheumatology, Allergy & Immunology, Richmond

27599

North Carolina Translational and Clinical Sciences Institute-Clinical & Translational Research Center (CTRC) at the University of North Carolina at Chapel Hill, Chapel Hill

30324

Emory University School of Medicine, Emory Healthcare: Emory Clinic Allergy and Immunology, Atlanta

33136

University Health, University of Miami Health System, Miami

33613

University of South Florida Asthma Allergy and Immunology Clinical Research Unit, Tampa

37232

Vanderbilt University Medical Center, Nashville

44195

Cleveland Clinic, Allergy & Clinical Immunology, Cleveland

48109

University of Michigan Health, Ann Arbor

48202

Henry Ford Hospital and Health System, Detroit

52242

University of Iowa Health Care, Iowa City

53792

University of Wisconsin Asthma Allergy Pulmonary Research, Madison

60077

NorthShore University HealthSystem, Dermatology Clinical Trials Unit, Skokie

60611

Sinus and Allergy Center of Northwestern University, Chicago

63104

Saint Louis University Care Center for Specialized Medicine, St Louis

72202

Arkansas Children's, University of Arkansas for Medical Sciences, Little Rock

75390

University of Texas Southwestern Medical Center, Dallas

77030

Baylor College of Medicine Medical Center, Houston

80206

National Jewish Health, Denver

85724

University of Arizona Health Sciences, College of Medicine Tucson, Department of Medicine, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Tucson

90095

University of California, Los Angeles Medical Center, Los Angeles

94040

Stanford Medicine, Sean N. Parker Center for Allergy & Asthma Research, Stanford

02114

Massachusetts General Hospital, Boston

02115

Brigham and Women's Hospital, Boston

All Listed Sponsors
collaborator

Immune Tolerance Network (ITN)

NETWORK

collaborator

Rho Federal Systems Division, Inc.

INDUSTRY

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT04761822 - COVID19 SARS Vaccinations: Systemic Allergic Reactions to SARS-CoV-2 Vaccinations | Biotech Hunter | Biotech Hunter