The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

115

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

June 1, 2023

Study Completion Date

June 1, 2023

Conditions
Arthroscopic Knee SurgeryRopivacaineCombined Spinal Epidurai AnesthesiaED50ED95
Interventions
DRUG

ropivacaine

According to previous clinical experience, 0.5% ropivacaine was given in the subarachnoid cavity, and the initial dose was set at 2.5 mL (12.5mg). Dixon's up-and down method was adopted to adjust or down-adjust the dose of ropivacaine in the next patient according to the experimental results of the previous patient, and the adjusted dose was 0.1 mL (0.5mg).

Trial Locations (1)

110000

Shengjing Hospital, Shengyang

All Listed Sponsors
lead

Yanchao Yang

OTHER

NCT04759742 - The Optimal Dosage of Ropivacaine for Arthroscopic Knee Surgery | Biotech Hunter | Biotech Hunter