Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population

NACompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

August 6, 2021

Study Completion Date

August 6, 2021

Conditions
VancomycinAdultArea Under Curve
Interventions
OTHER

Vancomycin dose adjustment using the Bayesian method

This intervention is the experimental method. The AUC/MIC target is 400-600 mg\*hour/L.

OTHER

Vancomycin dose adjustment using the trough level method

This intervention is the standard method. Previous clinical guidelines recommended this method. The trough target is 10-15 mg/L for non-severe infections and 15-20 mg/L for severe infections.

Trial Locations (1)

J4V 2H1

Charles-Le Moyne Hospital, Greenfield Park

All Listed Sponsors
lead

CR-CSSS Champlain-Charles-Le Moyne

OTHER

NCT04756895 - Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population | Biotech Hunter | Biotech Hunter