Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults

NACompletedINTERVENTIONAL
Enrollment

192

Participants

Timeline

Start Date

January 1, 2021

Primary Completion Date

June 30, 2021

Study Completion Date

January 9, 2023

Conditions
Dental CariesHydroxyapatiteTooth DecayDentin, CariousEnamel Caries
Interventions
OTHER

Experimental.

Tooth Brushing HAP 2x daily repeated cleaning of all teeth 3 min. using a standardized electric tooth brush Electric (powered) toothbrushes (Oral-B; P\&G, Schwalbach, Germany), brushing head: medium; will be changed every 2 months and a non-fluoridated tooth paste containing microcrystalline hydroxyapatite . HAP-toothpaste (Karex toothpaste with 10 % hydroxyapatite) If a subject shows multiple carious lesions during the course of the study, the study dentist will decide whether the subject must be excluded from the study. In this case the subject will receive additional intensive caries prophylactic measures (e.g. chlorhexi-dine gel application, dietary counselling, etc.). Caries preventive treatment (removing caries and placing a restoration) by the study centers is offered.

OTHER

Active comparator

Tooth Brushing F 2x daily repeated cleaning of all teeth 3min.using a standardized electric tooth brush ((Oral-B; P\&G, Schwalbach, Germany) and a fluoridated toothpaste (Karex Base with sodium fluoride 1450 F-), brushing head: medium; will be changed every 2 months If a subject shows multiple carious lesions during the course of the study, the study dentist will decide whether the subject must be excluded from the study. In this case the subject will receive additional intensive caries prophylactic measures (e.g. chlorhexidine gel application, dietary counselling, etc.). Caries preventive treatment (removing caries and placing a restoration) by the study centers is offered.

Trial Locations (1)

60-812

Poznan University of Medical Sciences, Poznan

All Listed Sponsors
collaborator

Medical University of Bialystok

OTHER

collaborator

Dr. Kurt Wolff GmbH & Co. KG

INDUSTRY

lead

Poznan University of Medical Sciences

OTHER

NCT04756557 - Caries-preventing Effect of a Hydroxyapatite-toothpaste in Adults | Biotech Hunter | Biotech Hunter