Mucolytics in Patients on Invasive Mechanical Ventilation Due to Severe Acute Respiratory Syndrome Coronavirus 2

NACompletedINTERVENTIONAL
Enrollment

175

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

July 1, 2021

Study Completion Date

July 29, 2021

Conditions
Corona Virus InfectionPneumonia, Ventilator-Associated
Interventions
OTHER

Inhalation of N-acetylcysteine

Group 1 will receive N-acetylcysteine inhalation every 12 hours from the beginning of invasive mechanical ventilation.

OTHER

Inhalation of 5% sodium chloride

Group 2 will receive inhalation with a 5% sodium chloride solution every 12 hours from the beginning of invasive mechanical ventilation.

OTHER

Inhalation of 8,4% sodium bicarbonate

Group 3 will receive inhalation of 8.4% sodium bicarbonate every 12 hours from the beginning of invasive mechanical ventilation.

Trial Locations (1)

21000

Clinical Hospital Centre Split, Split

All Listed Sponsors
lead

Clinical Hospital Center, Split

OTHER

NCT04755972 - Mucolytics in Patients on Invasive Mechanical Ventilation Due to Severe Acute Respiratory Syndrome Coronavirus 2 | Biotech Hunter | Biotech Hunter