Ticagrelor De-escalation Strategy in AMI Patients

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,312

Participants

Timeline

Start Date

March 27, 2023

Primary Completion Date

January 15, 2027

Study Completion Date

January 31, 2028

Conditions
Acute Myocardial Infarction
Interventions
DRUG

De-escalation strategy

De-escalation strategy indicates conventional DAPT (ticagrelor 90 mg twice daily + aspirin 100 mg once daily) for 1 month, followed by de-escalation DAPT (ticagrelor 60 mg twice daily + aspirin 100 mg once daily) between 1 and 3 months. Between 3 and 12 months, patients will be treated with ticagrelor monotherapy (ticagrelor 60 mg twice daily).

DRUG

Conventional strategy

Conventional stratetgy indicates conventional DAPT including ticagrelor 90 mg twice daily and aspirin 100 mg once daily during 12 months.

Trial Locations (1)

602-715

RECRUITING

DongA University Hospital, Busan

All Listed Sponsors
collaborator

Biotronik SE & Co. KG

INDUSTRY

collaborator

Samjin Pharmaceutical Co., Ltd.

INDUSTRY

lead

Dong-A University

OTHER

NCT04755387 - Ticagrelor De-escalation Strategy in AMI Patients | Biotech Hunter | Biotech Hunter