Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation

PHASE4CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

March 5, 2021

Primary Completion Date

May 1, 2021

Study Completion Date

May 1, 2021

Conditions
SedationIntubation
Interventions
DRUG

dexmedetomidine combined with midazolam and remifentanil.

Patients in this group will receive a bolus of midazolam 0.03 mg/kg intravenously, and then a loading dose of 0.5 mcg/kg remifentanil and 0.5 mcg/kg dexmedetomidine over 5 min via separate syringe pumps.

DRUG

propofol combined with midazolam and remifentanil.

Patients in this group will receive a bolus of midazolam 0.03 mg/kg intravenously, and then a loading dose of 0.5 mcg/kg remifentanil and 0.33 mg/kg propoful over 5 min via separate syringe pumps.

Trial Locations (1)

510655

the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Sixth Affiliated Hospital, Sun Yat-sen University

OTHER

NCT04753515 - Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation | Biotech Hunter | Biotech Hunter