Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

PHASE2CompletedINTERVENTIONAL
Enrollment

323

Participants

Timeline

Start Date

December 17, 2020

Primary Completion Date

December 7, 2021

Study Completion Date

December 7, 2021

Conditions
Primary Open Angle GlaucomaOcular Hypertension
Interventions
DRUG

DE-126 Ophthalmic Solution 0.002% QD

DE-126 Ophthalmic Solution QD evening and Vehicle QD Morning

DRUG

Timolol Maleate Ophthalmic Solution 0.5% BID

Timolol Maleate Ophthalmic Solution BID (morning and evening)

Trial Locations (41)

14618

Rochester Ophthalmological Group, P.C., Rochester

19107

Wills Eye Hospital, Philadelphia

27705

Duke Eye Center, Durham

30076

Coastal Research Associates, Roswell

30260

Clayton Eye Clinical Research, LLC, Morrow

32204

Levenson Eye Associates, Jacksonville

32224

Mayo Clinic, Dept. of Opthamology, Jacksonville

32258

Bowden Eye & Associates, Jacksonville

33773

Shettle Eye Research, Largo

45242

Apex Eye Clinical Research, LLC, Cincinnati

58078

Vance Thompson Vision - ND, West Fargo

79902

The Cataract and Glaucoma Center, El Paso

80045

University of Colorado, Dept. of Opthamology, Aurora

85050

Arizona Glaucoma Specialists, Phoenix

85224

Arizona Eye Center, Chandler

89119

Nevada Eye Care Professionals, Las Vegas

90013

Premiere Practice Management, Los Angeles

91105

University of California, Los Angeles, Doheny Eye Centers, Pasadena

91342

North Valley Eye Medical Group, Mission Hills

94954

North Bay Eye Associates, Inc, Petaluma

85351-3019

Walman Eye Center, Sun City

91204-2569

Global Research Management, Glendale

92663-3642

The Eye Research Foundation, Newport Beach

95815-4605

Sacramento Eye Consultants, Sacramento

34613-6065

Hernando Eye Institute, Brooksville

33901-9311

Eye Associates of Fort Myers, Fort Myers

31701-2363

Dixophthal PC dba Dixon Eye Care, Albany

01890

Clinical Eye Research of Boston, LLC, Winchester

89123-2810

AdvanceMed Clinical Research-Las Vegas, Las Vegas

07079-1855

Northern New Jersey Eye Institute, South Orange

27262-7612

Wake Forest Health Network Ophthamology - Oak Hollow, High Point

74104-5300

Office of Mark J. Weiss MD, Tulsa

16066-6412

Scott & Christie and Associates PC, Cranberry Township

57701-7374

Black Hills Regional Eye Institute, Rapid City

37803-6100

University Eye Specialists, Maryville

38120-9411

VRF Eye Specialty Group, Memphis

75231-2168

Glaucoma Associates of Texas, Dallas

78572-2425

DCT- Shah Research LLC dba Discovery Clinical Trials, Mission

78215-1936

San Antonio Eye Center, San Antonio

78229-3539

R and R Eye Research LLC, San Antonio

84117-5209

Stacy R. Smith M.D. P.C., Salt Lake City

All Listed Sponsors
lead

Santen Inc.

INDUSTRY

NCT04742283 - Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension | Biotech Hunter | Biotech Hunter