Subacute Effect of Pharyngeal Pharmacological Sensory Stimulation in Elderly Patients With Oropharyngeal Dysphagia

NACompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

January 17, 2019

Primary Completion Date

March 27, 2022

Study Completion Date

March 27, 2022

Conditions
Oropharyngeal DysphagiaDysphagiaSwallowing Disorder
Interventions
OTHER

Capsaicin 10microM (TRPV1 natural agonist)

10 mL Capsaicin 10microM solution 3 times per day (before each meal) during 14 consecutive days.

OTHER

Piperine 150microM (TRPV1 & TRPA1 natural agonist)

10 mL Piperine 150microM solution 3 times per day (before each meal) during 14 consecutive days.

OTHER

Cinnamaldehyde 756,6microM + zinc 70microM (TRPA1 natural agonist)

10 mL Cinnamaldehyde 756,6microM + zinc 70microM solution 3 times per day (before each meal) during 14 consecutive days.

OTHER

Citric acid 457,5microM (pH=3,5) (ASIC3 natural agonist)

10 mL Citric acid 457,5microM (pH=3,5) solution 3 times per day (before each meal) during 14 consecutive days.

OTHER

Capsaicin 10microM + Citric acid 457,5microM (pH=3,5) (TRPV1 & ASIC3 natural agonists)

10 mL Capsaicin 10microM + Citric acid 457,5microM (pH=3,5) solution 3 times per day (before each meal) during 14 consecutive days.

OTHER

Placebo (Methyl benzoate, Propyl benzoate, Propylenglycol)

10 mL placebo solution 3 times per day (before each meal) during 14 consecutive days.

Trial Locations (1)

08301

Consorci Sanitari del Maresme (Hospital de Mataró), Mataró

All Listed Sponsors
lead

Hospital de Mataró

OTHER

NCT04741620 - Subacute Effect of Pharyngeal Pharmacological Sensory Stimulation in Elderly Patients With Oropharyngeal Dysphagia | Biotech Hunter | Biotech Hunter