Individualized PEEP in Thoracic Surgery

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 4, 2021

Primary Completion Date

December 4, 2021

Study Completion Date

December 5, 2021

Conditions
Thoracic SurgeryOne-lung VentilationRespiratory MechanicsArtificial Respiration
Interventions
PROCEDURE

Best PEEP

In OLV, the investigator will perform a PEEP decremental titration trial, decreasing PEEP from 16 to 4 cmH2O (steps of 2-cmH2O, lasting 1 minute). At the end of every step driving pressure (Pplat-PEEP) will be calculated, and the PEEP corresponding to the lowest driving pressure + 2cmH2O will be set.

PROCEDURE

Standard PEEP

In OLV, a PEEP of 5 cm H2O will be set.

Trial Locations (1)

34149

Azienda Sanitaria Universitaria Giuliano-Isontina, Cattinara Hospital, Trieste

All Listed Sponsors
lead

University of Trieste

OTHER

NCT04740151 - Individualized PEEP in Thoracic Surgery | Biotech Hunter | Biotech Hunter