Efficacy and Safety of UC-MSCs for the Treatment of Steroid-resistant aGVHD Following Allo-HSCT

PHASE3CompletedINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

February 1, 2021

Primary Completion Date

May 30, 2022

Study Completion Date

May 2, 2023

Conditions
Graft Vs Host Disease
Interventions
DRUG

UC-MSC

UC-MSC, iv, 1×10\^6 cells/kg, once a week, for 4 weeks.

DRUG

Anti-CD25 mAb

Anti-CD25 mAb, iv, 20mg,twice in first week and once a week thereafter, for 4 weeks.

Trial Locations (1)

100010

Peking University Insititute of Hematology, Peking University People's Hospital, Beijing

All Listed Sponsors
collaborator

Southern Medical University, China

OTHER

collaborator

Third Military Medical University

OTHER

collaborator

Sun Yat-sen University

OTHER

lead

Peking University People's Hospital

OTHER

NCT04738981 - Efficacy and Safety of UC-MSCs for the Treatment of Steroid-resistant aGVHD Following Allo-HSCT | Biotech Hunter | Biotech Hunter