A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

349

Participants

Timeline

Start Date

January 11, 2021

Primary Completion Date

March 25, 2022

Study Completion Date

March 25, 2022

Conditions
Dry Eye Disease
Interventions
DRUG

SURF-100 (Combination of 0.3% Mycophenolic Acid and 0.01% Betamethasone Sodium Phosphate)

combination of a topical immunosuppressant and a topical corticosteroid solution

DRUG

Mycophenolic Acid 0.1%

topical immunosuppressant

DRUG

Mycophenolic Acid 0.3%

topical immunosuppressant

DRUG

Betamethasone Sodium Phosphate 0.01%

topical corticosteroid solution

DRUG

Placebo Comparator: Vehicle

topical vehicle solution

DRUG

Cyclosporine 0.05% Ophthalmic Emulsion

topical ophthalmic emulsion

DRUG

Lifitegrast 5% Ophthalmic Solution

topical ophthalmic solution

Trial Locations (40)

12603

Alterman, Modi & Wolter, Poughkeepsie

14618

Rochester Ophthalmological Group, PC, Rochester

16066

Scott & Christie and Associates, PC, Cranberry Township

27401

Physicians Protocol, Greensboro

30076

Coastal Research Associates, LLC, Roswell

32162

Blue Ocean Clinical Research at The Macula Center, The Villages

32256

Bowden Eye and Associates, Jacksonville

32405

Eye Center of North Florida PA, Panama City

33426

Florida Eye Microsurgical Institute, Inc., Boynton Beach

33603

International Research Center, Tampa

34613

Hernando Eye Institute, Brooksville

37215

West TN EyeCare dba Toyos Clinic, Nashville

38119

Total Eye Care, PA, Memphis

38120

VRF Eye Specialty Group, Memphis

40517

Kentucky Eye Institute, Lexington

41017

Cincinnati Eye Institute, Edgewood

57701

Black Hills Regional Eye Institute, Rapid City

60046

Jackson Eye, Lake Villa

63017

Midwest Vision Research Foundation at Pepose Vision Institute, Chesterfield

63128

Tekwani Vision Center, St Louis

63131

Ophthalmology Consultants Ltd., St Louis

64111

Tauber Eye Center, Kansas City

77025

Houston Eye Associates, Houston

77034

Advanced Laser Vision & Surgical Institute, Houston

78209

Eye Clinics of South Texas, PA, San Antonio

78229

R and R Eye Research, LLC, San Antonio

78731

Texan Eye Care, PA - Keystone Research, Ltd, Austin

80528

The Eye Center of Northern Colorado, Fort Collins

84041

Tanner Clinic, Layton

84107

The Eye Institute of Utah, Salt Lake City

85032

Cornea and Cataract Consultants of Arizona PC, Phoenix

91345

North Valley Eye Medical Group Inc., Mission Hills

91702

Canyon City EyeCare, Azusa

92545

Inland Eye Specialists, Hemet

92562

LoBue Laser and Eye Medical Center, Murrieta

92663

Eye Research Foundation, Newport Beach

95670

Martel Eye Medical Group, Rancho Cordova

95815

Sacramento Eye Consultants, A Medical Corporation, Sacramento

06810

Connecticut Eye Consultants, PC, Danbury

03878

EyeSight Ophthalmic Services, Somersworth

All Listed Sponsors
lead

Surface Ophthalmics, Inc.

INDUSTRY

NCT04734197 - A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye Disease | Biotech Hunter | Biotech Hunter