A Study of the Efficacy and Safety of Frespaciguat (MK-5475) in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)

Sanatorio de la Trinidad Mitre ( Site 0130), Buenos Aires

Greenlane Clinical Centre ( Site 0203), Auckland

Université Libre de Bruxelles - Hôpital Erasme ( Site 0601), Brussels

Hospital El Cruce Nestor Carlos Kirchner ( Site 0132), San Juan Bautista

Macquarie University ( Site 0180), Macquarie University

John Hunter Hospital ( Site 0185), Newcastle

Nepean Hospital ( Site 0184), Kingswood

UZ Leuven ( Site 0600), Leuven

Christchurch Hospital ( Site 0201), Christchurch

Instituto Nacional de Cardiología -Ignacio Chavez ( Site 0651), Mexico City

Georgetown University Hospital ( Site 0025), Washington D.C.

Centro Cardiologico Monzino IRCCS ( Site 0306), Milan

Ospedale San Gerardo - ASST Monza ( Site 0304), Monza

University of Maryland ( Site 0032), Baltimore

Sentara Norfolk General Hospital ( Site 0014), Norfolk

Eskisehir Osmangazi Uni. Tip Fakultesi Hastanesi ( Site 0506), Eskişehir

West Virginia University-WVU Heart and Vascular Institute ( Site 0051), Morgantown

Fondazione IRCCS Policlinico San Matteo ( Site 0302), Pavia

Clinical Trials Unit at Eastowne Medical Office Building ( Site 0019), Chapel Hill

CHRU Brest - Hopital Cavale Blanche ( Site 0254), Brest

AnMed Health ( Site 0033), Anderson

Medizinische Hochschule Hannover ( Site 0284), Hanover

CHU de Toulouse - Hopital Larrey ( Site 0258), Toulouse

AdventHealth Orlando ( Site 0040), Orlando

University of Miami Hospital-Division of Pulmonary & Critical Care ( Site 0053), Miami

Tampa General Hospital ( Site 0058), Tampa

Istanbul Uni. Kardiyoloji Enstitusu ( Site 0502), Istanbul

Istanbul Universitesi Istanbul Tip Fakultesi ( Site 0509), Istanbul

Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi ( Site 0501), Istanbul

Ege Universitesi Hastanesi-Cardilogy Department ( Site 0504), Bornova

Dokuz Eylul University Faculty of Medicine ( Site 0505), Izmir

UKGM Gießen/Marburg ( Site 0279), Giessen

Statcare Pulmonary Consultants ( Site 0067), Knoxville

Norton Pulmonary Specialists ( Site 0048), Louisville

University of Kentucky ( Site 0006), Lexington

University of Iowa Hospital and Clinics ( Site 0009), Iowa City

Operadora de Hospitales Angeles. S.A. de C.V. -Sucursal Lomas ( Site 0653), Huixquilucan

AHEPA University General Hospital of Thessaloniki ( Site 0577), Thessaloniki

Institut Coeur Poumon - CHRU de Lille ( Site 0252), Lille

Washington University School of Medicine ( Site 0066), St Louis

University of Kansas Medical Center ( Site 0038), Kansas City

University of Nebraska Medical Center ( Site 0041), Omaha

Thoraxklinik Heidelberg gGmbH am Universitaetsklinikum Heidelberg ( Site 0276), Heidelberg

University of Texas Southwestern Medical Center at Dallas ( Site 0012), Dallas

Centre Hospitalier Universitaire de Rouen ( Site 0253), Rouen

Houston Methodist Research Institute ( Site 0036), Houston

The University of Texas Health Science Center at Houston ( Site 0054), Houston

University of Colorado - Denver ( Site 0003), Aurora

University of Naples Federico II ( Site 0308), Naples

Cardiovascular Institute of North Colorado - Banner Health ( Site 0013), Greeley

University of New Mexico, Health Sciences Center ( Site 0028), Albuquerque

Consultorio 1020 Hospital Angeles Xalapa ( Site 0654), Xalapa

UCSF Helen Diller Medical Center at Parnassus Heights ( Site 0063), San Francisco

CHU - Hopital de Bicetre ( Site 0251), Le Kremlin-Bicêtre

University of California Davis Health-Internal Medicine: Pulmonary, Critical Care and Sleep Medicine, Sacramento

Klinikum Würzburg Mitte-Medizinische Klinik - Schwerpunkt Pneumologie & Beatmungsmedizin ( Site 0280, Würzburg

Hospital Universitario San Ignacio ( Site 0152), Bogotá

Almazov National Medical Research Centre of the Ministry of Health ( Site 0402), Saint Petersburg

Scientific Research Institute Complex Problems Cardiovascular Disease ( Site 0403), Kemerovo

Fundacion Cardiovascular de Colombia ( Site 0155), Piedecuesta

Rambam Medical Center ( Site 0335), Haifa

Rabin Medical Center ( Site 0327), Petah Tikva

Wolfson Medical Center [Holon, Israel] ( Site 0333), Holon

Soroka Medical Center ( Site 0330), Beersheba

Shaare Zedek Medical Center ( Site 0331), Jerusalem

University of California San Diego Health-Pulmonary Critical Care ( Site 0061), La Jolla

Indiana University Health Methodist Hospital ( Site 0045), Indianapolis

Cardiologia Palermo ( Site 0140), Ciudad Autonoma de Buenos Aires

Centro Medico Capital ( Site 0131), La Plata

Hospital Universitario Austral ( Site 0138), Pilar

Instituto de Investigaciones Clinicas Quilmes ( Site 0141), Quilmes

Instituto Cardiovascular de Rosario ( Site 0128), Rosario

Hospital Privado Universitario de Córdoba ( Site 0137), Córdoba

Peter Lougheed Centre ( Site 0107), Calgary

University Health Network - Toronto General Hospital ( Site 0104), Toronto

IUCPQ ( Site 0111), Québec

Centro Cardiovascular Colombiano Clínica Santa María ( Site 0154), Medellín

Uniklinikum Dresden ( Site 0283), Dresden

Universitaetsklinikum Leipzig ( Site 0285), Leipzig

Azienda Ospedaliera Policlinico Umberto I ( Site 0301), Rome

Krakowski Szpital Specjalistyczny im. Jana Pawa II-Oddzial Kliniczny Chorob Serca i Naczyn z Pododd, Krakow

Specjalistyczny Szpital im. Dr Alfreda Sokolowskiego w Walbrzychu ( Site 0351), Wałbrzych

Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie ( Site 0352), Lublin

Akademiska sjukhuset ( Site 0453), Uppsala

Sahlgrenska Universitetssjukhuset-Cardiology Research Unit ( Site 0452), Gothenburg

Hacettepe Universitesi Tip Fakultesi Hastanesi ( Site 0510), Ankara

Akdeniz Uni.Tip Fakultesi Saglik Uygulama ve Arastirma Merkezi ( Site 0508), Antalya

Golden Jubilee National Hospital ( Site 0556), Glasgow

Royal Brompton and Harefield NHS Trust ( Site 0553), London

Imperial College Healthcare NHS Trust - Hammersmith Hospital ( Site 0554), London

The Freeman Hosp.Newcastle upon Tyne Hosp NHS Trust ( Site 0552), Newcastle upon Tyne