Median Nerve Stimulation Pilot

NACompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

July 15, 2021

Primary Completion Date

April 27, 2022

Study Completion Date

April 27, 2022

Conditions
Tourette SyndromeTic DisordersTic Disorder, Chronic Motor or Vocal
Interventions
DEVICE

Rhythmic median nerve stimulation

Square-wave 200 µs pulses triggered by computer at 12 Hz, at the threshold for thumb movement (expected \~2-15mA), applied to surface electrodes over the median nerve at the right wrist (conductive gel, 30 mm apart center-to-center, anode distal). This is a non-significant risk device study.

DEVICE

Arrhythmic median nerve stimulation

Square-wave 200 µs pulses triggered by computer at random intervals with a mean rate of 12 Hz (as described in Morera Maiquez et al., 2020), at the threshold for thumb movement (expected \~2-15mA), applied to surface electrodes over the median nerve at the right wrist (conductive gel, 30 mm apart center-to-center, anode distal). This is a non-significant risk device study.

Trial Locations (1)

63110

Washington University School of Medicine, Movement Disorders Center, St Louis

All Listed Sponsors
collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

lead

Washington University School of Medicine

OTHER