The Effect of Dual Eradication Therapy vs PPI on Gastrointestinal Bleeding in ACS Patients

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,600

Participants

Timeline

Start Date

April 12, 2023

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Acute Coronary SyndromeHelicobacter Pylori Infection
Interventions
DRUG

Vonoprazan-based dual eradication therapy for two weeks

Patients with ACS after PCI, associated with positive Hp need a long-term DAPT treatment. We conducted a study on the prevention of gastrointestinal bleeding between vonoprazan-based dual eradication therapy for two weeks and pantoprazole for six months of a rountine therapy.

DRUG

amoxicillin

amoxicillin

DRUG

Pantoprazole

Pantoprazole

Trial Locations (42)

100012

RECRUITING

Aviation General Hospital, Beijing

100029

RECRUITING

China-Japan Friendship Hospital, Beijing

200000

NOT_YET_RECRUITING

The Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai

230000

NOT_YET_RECRUITING

The First Affiliated Hospital of Anhui Medical University, Hefei

236800

RECRUITING

Bozhou People's Hospital, Bozhou

239000

RECRUITING

Chuzhou First People's Hospital, Chuzhou

250000

WITHDRAWN

The 960th Hospital of the Joint Logistic Support Force, Jinan

250002

WITHDRAWN

Shandong Second Provincial General Hospital, Jinan

250011

RECRUITING

Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan

250012

NOT_YET_RECRUITING

Qilu Hospital of Shandong University, Jinan

250031

RECRUITING

Shandong Provincial Third Hospital, Jinan

RECRUITING

The fourth People's Hospital of jinan, Jinan

250100

RECRUITING

Shandong Public Health Clinical Center, Jinan

252000

NOT_YET_RECRUITING

Liaocheng People's Hospital, Liaocheng

253000

RECRUITING

Qilu Hospital of Shandong University Dezhou Hospital, Dezhou

253100

RECRUITING

Pingyuan First People'S Hospital, Dezhou

253400

RECRUITING

NINGJIN People's Hospital, Dezhou

255000

WITHDRAWN

Zibo Central Hospital, Zibo

256100

RECRUITING

Haiyang People's Hospital, Yantai

257091

RECRUITING

Dongying People's Hospital, Dongying

257335

RECRUITING

THE Second People's Hospital of Dongying, Dongying

261031

RECRUITING

Affiliated Hospital of Shandong Second Medical University, Weifang

261041

RECRUITING

Weifang Hospital of Traditional Chinese Medicine, Weifang

264200

WITHDRAWN

Weihai Central Hospital, Weihai

NOT_YET_RECRUITING

Weihai Municipal Hospital, Weihai

264500

RECRUITING

Ru Shan People's Hospital, Rushan

266000

NOT_YET_RECRUITING

Qilu Hospital of Shandong University (Qingdao), Qingdao

266003

RECRUITING

The Affiliated Hospital of Qingdao University, Qingdao

271199

RECRUITING

JINA CITY People's Hospital, Jinan

272000

NOT_YET_RECRUITING

The First People's Hospital of Jining City, Jining

274031

RECRUITING

Heze Municipal Hospital, Heze

276000

NOT_YET_RECRUITING

Linyi City People's Hospital, Linyi

276700

RECRUITING

Linshu County People'S Hospital, Linyi

277000

WITHDRAWN

Shandong Healthcare Group Zaozhuang Central Hospital, Zaozhuang

277100

RECRUITING

Zaozhuang Municipal Hospital, Zaozhuang

300222

WITHDRAWN

Tianjin Chest Hospital, Tianjin

450052

RECRUITING

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

563000

RECRUITING

The First People'S Hospital of Zunyi, Zunyi

610072

WITHDRAWN

Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu

810000

RECRUITING

Qinghai Red Cross Hospital, Xining

Unknown

RECRUITING

The First Affiliated Hospital of Dalian Medical University, Dalian

WITHDRAWN

Central Hospital Affiliated to Shandong First medical University, Jinan

All Listed Sponsors
lead

Qilu Hospital of Shandong University

OTHER