The Effect of Opioid-Free Anesthesia in TMJ Surgery

PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 18, 2021

Primary Completion Date

April 23, 2023

Study Completion Date

April 23, 2023

Conditions
Temporomandibular Joint Disorders
Interventions
DRUG

Dexmedetomidine / Ketamine / Lidocaine

Patients in this group will receive an infusion of lidocaine, ketamine, or dexmedetomidine supplemented with other intravenous analgesics and intravenous and inhaled anesthetics, as needed clinically. This includes administration of 5 mcg/kg/min of ketamine plus 0.5 - 1.0 µg/kg/hr of dexmedetomidine (Precedex) as a continuous infusion, started from induction to stop one hour before surgery is anticipated to end.

Trial Locations (1)

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER