Efficacy of Mouthwashes in Reducing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load in the Saliva

NACompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

May 19, 2021

Primary Completion Date

October 25, 2021

Study Completion Date

October 25, 2021

Conditions
Covid19Coronavirus
Interventions
DRUG

Corsodyl® Alcohol free -0.2 % Chlorhexidine digluconate

Corsodyl® Alcohol-free is a clear to slightly opalescent oromucosal solution with an odour of peppermint that contains 0.2% w/v chlorhexidine digluconate which is an antimicrobial preparation for external use. It is effective against a wide range of Gram negative and Gram positive vegetative bacteria, yeasts, dermatophyte fungi and lipophilic viruses. It is active against a wide range of important oral pathogens and is therefore effective in the treatment of many common oral conditions.

DRUG

Colgate Peroxyl® -1.5% Hydrogen peroxide

Peroxyl mouthwash is a clear aqua-blue liquid oromucosal solution which 100ml of solution contains 1.5g of Hydrogen peroxide (as 30% Hydrogen Peroxide solution). It is an oral antiseptic cleanser for external use. The principal action is brought about by contact of hydrogen peroxide with peroxidases and catalases present in tissues and saliva, which causes the rapid release of oxygen. This provides mechanical cleansing which flushes out mouth debris and helps in the treatment of oral irritations. This mouthwash is used as a cleanser in the symptomatic relief of minor mouth and gum irritations.

OTHER

Oral-B® Gum & Enamel Care -Cetylpyridinium chloride

The Oral-B® Gum \& Enamel Care mouthwash is an oromucosal solution containing Cetylpyridinium chloride (CPC) and used as an adjunct to oral hygiene.

OTHER

No rinsing

No rinsing

Trial Locations (2)

Unknown

Newham Hospital, London

Royal London Hospital, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

GlaxoSmithKline

INDUSTRY

lead

Queen Mary University of London

OTHER

NCT04723446 - Efficacy of Mouthwashes in Reducing Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Viral Load in the Saliva | Biotech Hunter | Biotech Hunter