Topical Antisepsis in Head and Neck Cancer Surgery

CompletedOBSERVATIONAL
Enrollment

25

Participants

Timeline

Start Date

January 6, 2021

Primary Completion Date

May 28, 2021

Study Completion Date

October 4, 2021

Conditions
Head and Neck Cancer
Interventions
DRUG

Chlorhexidine Gluconate

"Preoperative: The patient's dentition, or mandibular alveolus in the absence of dentition, will be brushed for two minutes with 0.12% chlorhexidine gluconate.~Intraoperative: The wound will be irrigated for 60 seconds with 0.05% chlorhexidine after it is irrigated with povidone-iodine.~Postoperative: Patients will swish and spit/suction 15mL 0.12% Chlorhexidine Gluconate (CHG) oral rinses for 30 seconds every six hours for two days (8 total administrations)"

DRUG

Povidone-iodine

"Preoperative: The oral cavity and oropharyngeal mucosa as well as the nasal vestibules will be coated with 5% povidone-iodine which will stand for at least three minutes prior to incision.~Intraoperative: The wound will be irrigated for 60 seconds with 10% povidone-iodine."

DRUG

Tetracycline Ointment

Postoperative: \~10g 3% tetracycline ointment will be placed into the oral cavity to coat the dorsal tongue and any oral suture lines every six hours for two days (8 total doses).

Trial Locations (1)

53226

Froedtert Hospital & the Medical College of Wisconsin, Milwaukee

All Listed Sponsors
lead

Medical College of Wisconsin

OTHER

NCT04721626 - Topical Antisepsis in Head and Neck Cancer Surgery | Biotech Hunter | Biotech Hunter