NCT04717336View on ClinicalTrials.gov

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT)

NACompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

January 22, 2021

Primary Completion Date

June 30, 2022

Study Completion Date

July 8, 2022

Conditions
Cardiovascular Disease
Interventions
OTHER

Sodium Chloride

It is well established that increased dietary sodium can predispose to an increase in blood pressure; particularly in salt-sensitive individuals. Seeking to test the hypothesis that changes in dietary sodium intake are sufficient to influence the composition of the gut microbiome in association with sodium-induced changes in vascular function, epigenome, transcriptome and blood pressure in African Americans.

OTHER

Placebo

placebo capsules

Trial Locations (1)

20892

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
collaborator

National Human Genome Research Institute (NHGRI)

NIH

lead

National Heart, Lung, and Blood Institute (NHLBI)

NIH

NCT04717336 - Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENE-FORECAST): Sodium Intervention Trial (SIT) | Biotech Hunter | Biotech Hunter