24
Participants
Start Date
February 1, 2021
Primary Completion Date
May 31, 2023
Study Completion Date
May 31, 2023
Normobaric hypoxia (FiO2 15%)
"Inhalation of deoxygenated air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise."
Placebo-ambient air (FiO2 21%)
"Inhalation of room air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise."
Normobaric hypoxia (FiO2 15%) under Sildenafil
"Inhalation of deoxygenated air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise under Sildenafil."
Placebo-ambient air (FiO2 21%) under Sildenafil
"Inhalation of room air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise under Sildenafil."
University Hospital of Zurich, Zurich
University of Zurich
OTHER