856
Participants
Start Date
November 2, 2023
Primary Completion Date
August 28, 2025
Study Completion Date
October 23, 2025
20-25% Albumin fluid (100 mL)
"Participants will be randomized to receive albumin (20-25%) during their RRT sessions (either CRRT, SLED or IHD) in ICU. Once randomized the same fluid will be given for all subsequent RRT sessions for up to 14 days in ICU.~RRT sessions will be determined as per the treating physician. Boluses will be given at the start of, and halfway through, RRT sessions (i.e. for SLED sessions, at 0 and 4 hours; for IHD sessions, at 0 and 2 hours)."
0.9% Normal Saline (100 mL)
"Participants will be randomized to receive normal saline 100 mL boluses during their RRT sessions (either CRRT, SLED or IHD) in ICU. Once randomized the same fluid will be given for all subsequent RRT sessions for up to 14 days in ICU.~RRT sessions will be determined as per the treating physician. Boluses will be given at the start of, and halfway through, RRT sessions (e.g. for 8 hour SLED sessions, at 0 and 4 hours; for 4 hour IHD sessions, at 0 and 2 hours; for CRRT, after starting/randomization then every 12 hours while continuing on CRRT)."
NOT_YET_RECRUITING
The Governors of the University of Calgary, Calgary
NOT_YET_RECRUITING
University of Manitoba - Health Sciences Centre, Winnipeg
NOT_YET_RECRUITING
Nova Scotia Health Authority, Halifax
RECRUITING
Hamilton Health Sciences Corporation, Hamilton
NOT_YET_RECRUITING
Scarborough Health Network, Scarborough Village
RECRUITING
Centre Integre Universitaire de Sante et de Services Sociaux de L'Estrie - Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke
NOT_YET_RECRUITING
University of Saskatchewan, Saskatoon
RECRUITING
Kingston General Hospital, Kingston
RECRUITING
Sunnybrook Health Sciences Centre, North York
RECRUITING
The Ottawa Hospital, Ottawa
RECRUITING
University of Ottawa Heart Institute, Ottawa
RECRUITING
Niagara Health System, St. Catharines
NOT_YET_RECRUITING
St. Michael's Hospital, Toronto
RECRUITING
Sinai Health System, Toronto
NOT_YET_RECRUITING
Lakeridge Health, Whitby
RECRUITING
Centre Integre de Sante et de Services Sociaux de Laval, Laval
Lead Sponsor
The Physicians' Services Incorporated Foundation
OTHER
The Kidney Foundation of Canada
OTHER
The Ottawa Hospital Academic Medical Organization (TOHAMO) Innovation Fund Grant.
UNKNOWN
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
Canadian Blood Services
OTHER
Héma-Québec
OTHER
Ottawa Hospital Research Institute
OTHER