NCT04704440 - Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension With/Without Sildenafil | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

February 1, 2021

Primary Completion Date

May 31, 2023

Study Completion Date

May 31, 2023

Conditions

Hypertension, Pulmonary

Interventions

OTHER

Normobaric hypoxia (FiO2 15%)

"Inhalation of deoxygenated air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise."

OTHER

Placebo-ambient air (FiO2 21%)

"Inhalation of room air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise."

OTHER

Normobaric hypoxia (FiO2 15%) under Sildenafil

"Inhalation of deoxygenated air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise."

OTHER

Placebo-ambient air (FiO2 21%) under Sildenafil

"Inhalation of room air through an altitude simulator (Altitrainer), for approx. 1/2 hour given by a facemask, first at rest and then during exercise."

Trial Locations (1)

8091

University Hospital of Zurich, Zurich

All Listed Sponsors

lead

University of Zurich

OTHER