Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects

RecruitingOBSERVATIONAL
Enrollment

80

Participants

Timeline

Start Date

July 18, 2022

Primary Completion Date

April 18, 2026

Study Completion Date

April 18, 2026

Conditions
Amelogenesis ImperfectaDental FluorosesHypomineralization Molar Incisor
Interventions
OTHER

spectrophotometer

"* Calibration of the spectrophotometer (calibration of white and green color on the provided support),~* Placing the patient or witness in the chair,~* Placement of intraoral retractors,~* Photographs of the dental arch in occlusion as well as slightly open mouth to visualize the mandibular incisors,~* If MIH is suspected, occlusal images of the occlusal surfaces of the first molars will be taken with the help of a dental mirror,~* Shooting with the spectrophotometer centered on each of the teeth of interest in the anterior sector with verification of the good quality of the shot according to the axis (validated in green on the camera),~* Backup of images with coded identification number"

OTHER

Biological (protein analysis by western blot or mass spectrometry of matrix proteins), structural (electron microscopy) and physico-chemical analyses

"* Chemical analysis of enamel mineral.~* Techniques of spectrometry and spectroscopy (Raman and FTIR)~* Atomic Probe Tomography and Protein Mass Spectrometry (ICP-MS)."

Trial Locations (1)

75013

RECRUITING

Service d'odontologie, Hôpital Pitié-Salpêtrière, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER