Study of the Effects of Anticoagulant Interruption Covered by Percutaneous Left Atrial Occlusion in Patients With Chronic Atrial Fibrillation and Radiation Cystitis at Risk of Bleeding

RecruitingOBSERVATIONAL
Enrollment

40

Participants

Timeline

Start Date

February 24, 2021

Primary Completion Date

January 31, 2029

Study Completion Date

September 30, 2030

Conditions
Radiation CystitisNon-valvular Atrial Fibrillation
Interventions
DEVICE

Percutaneous left atrial closure

Percutaneous left atrial closure was performed under general anesthesia with angiographic control and transesophageal echocardiography. The procedure takes between 15 and 20 minutes. This begins with a right femoral venipuncture, progression of the guide in the right atrium allowing atrial trans-septal puncture to catheterize the left atrium. A nitinol prosthesis is implanted (Boston Watchman) at the ostium of the left auricle between the left superior pulmonary vein and the circumflex artery. After a tensile test verifying the stability of the prosthesis, the absence of peri-prosthetic leakage is verified by ETO and angiographic control. The patient is monitored 48 hours before discharge to eliminate the appearance of pericardial effusion and prosthetic embolization. Aspirin 75 mg monotherapy is started the same day with stopping anticoagulation.

OTHER

No Percutaneous left atrial closure

No Percutaneous left atrial closure

Trial Locations (1)

63003

RECRUITING

Chu Clermont Ferrand, Clermont-Ferrand

All Listed Sponsors
lead

University Hospital, Clermont-Ferrand

OTHER