Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

536

Participants

Timeline

Start Date

March 1, 2021

Primary Completion Date

August 18, 2021

Study Completion Date

September 22, 2021

Conditions
TrichuriasisAscariasisHookworm InfectionsHelminthes; Infestation, Intestinal
Interventions
DRUG

moxidectin (8 mg) / albendazole (400 mg)

Combination therapy of moxidectin (8 mg using 2 mg tablets) plus albendazole (Zentel®, 400 mg, single tablet) administered orally at day 0

DRUG

ivermectin (200 µg/kg) / albendazole (400 mg)

Combination therapy of ivermectin ((200 µg/kg), 3 mg tablet) plus albendazole (Zentel®, 400 mg, single tablet) administered orally at day 0

DRUG

ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL]

Monotherapy of albendazole (Zentel®, 400 mg, single tablet) administered orally at day 0

DRUG

ivermectin (200 µg/kg)

Monotherapy of ivermectin ((200 µg/kg), 3 mg tablet) administered orally at day 0

DRUG

moxidectin (8 mg)

Monotherapy of moxidectin (8 mg, using 2 mg tablets) administered orally at day 0

Trial Locations (1)

Unknown

Public Health Laboratory Ivo de Carneri, Chake Chake

All Listed Sponsors
collaborator

Public Health Laboratory Ivo de Carneri

OTHER

lead

Jennifer Keiser

OTHER

NCT04700423 - Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration | Biotech Hunter | Biotech Hunter