Application of Platelet-rich Plasma in Pilonidal Sinus Disease

NACompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

March 1, 2018

Primary Completion Date

January 1, 2019

Study Completion Date

July 1, 2019

Conditions
Pilonidal SinusPilonidal DiseaseWound HealQuality of LifePain
Interventions
PROCEDURE

Open surgery

Each patient entered the operating room, and after the administration of general anaesthesia, the patient was placed in the prone position. Then, the buttocks were stretched to the lateral sides using adhesive bands to remove the disease area. The sacrococcygeal region was cleaned and disinfected with 10% povidone iodine. After covering the area around the region, the sinus tract was examined by using a thin-steel cane. The length and wealth of the cavity were noted. Then, the sinus tract was removed. The depth of the cavity was noted. Then, 50 cc of 0.9% saline solution (SS) was taken into a syringe and applied to the cavity until it filled the whole space, allowing the cavity volume to be measured accurately. The measurement was performed by subtracting the remaining saline-solution volume in the syringe from the whole syringe volume, which was 50 cc.

PROCEDURE

Minimal invasive surgery

In the operating room, after the patient was placed in the prone position, the region was removed by stretching the buttocks with adhesive bands and cleaning the area with 10% povidone iodine. The largest pit was excised, and hairs in the cavity were removed with forceps. Then, the whole cavity was curetted meticulously and irrigated with SS. After haemostasis, the cavity volume was measured

OTHER

Platelet rich plasma administration

Platelet rich plasma (PRP) was administered by filling the whole space from the lateral side of the cavity. After the first implementation of PRP, the second one was applied at 48 hours. Until that time, the dressing was not uncovered. PRP was applied on the 3rd, 4th and 5th days postoperatively.

Trial Locations (1)

06100

Ankara University School of Medicine Department of General Surgery, Ankara

All Listed Sponsors
lead

Cihangir Akyol

OTHER

NCT04697082 - Application of Platelet-rich Plasma in Pilonidal Sinus Disease | Biotech Hunter | Biotech Hunter