M1231 in Participants With Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

January 13, 2021

Primary Completion Date

June 23, 2023

Study Completion Date

June 23, 2023

Conditions
Metastatic Solid TumorsEsophageal CancerNon-Small Cell Lung Cancer
Interventions
DRUG

M1231

M1231 will be administered at escalated doses every three weeks until disease progression, unacceptable toxicity, withdrawal of consent, or any criterion for withdrawal from the study.

DRUG

M1231

M1231 will be administered at the dose determined as RDE in part 1, every three weeks until disease progression, unacceptable toxicity, withdrawal of consent, or any criterion for withdrawal from the study.

Trial Locations (3)

77030

MD Anderson Cancer Center - Clinical Cancer Prevention, Houston

78229

NEXT Oncology, San Antonio

Unknown

Princess Margaret Cancer Centre, Toronto

All Listed Sponsors
lead

EMD Serono Research & Development Institute, Inc.

INDUSTRY

collaborator

Merck KGaA, Darmstadt, Germany

INDUSTRY

NCT04695847 - M1231 in Participants With Solid Tumors | Biotech Hunter | Biotech Hunter