Restore Resilience in Critically Ill Children

NACompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

September 5, 2017

Primary Completion Date

December 31, 2021

Study Completion Date

December 31, 2021

Conditions
Acute Respiratory Distress Syndrome
Interventions
OTHER

R2 Bundle

"During the intervention phase subjects will receive R2.~1. Focused effort to replicate the child's pre-hospitalization daily routine (bedtime/wake time, bedtime/arousal routine, nap time, feeding schedule, active periods),~2. Cycled day-night lighting and modulation of sound to match the child's routine,~3. Minimal yet effective sedation using a nurse-implemented goal-directed sedation plan (RESTORE),~4. Night fasting with bolus enteral daytime feedings,~5. Early, developmentally-appropriate, progressive exercise and mobility (PICU Up!),~6. Continuity in nursing care, and~7. Parent diaries."

Trial Locations (2)

19104

Children's Hospital of Philadelphia, Philadelphia

21287

Johns Hopkins University - Charlotte Bloomberg Children's Center, Baltimore

All Listed Sponsors
collaborator

Johns Hopkins University

OTHER

collaborator

Children's Hospital of Philadelphia

OTHER

collaborator

Boston Children's Hospital

OTHER

lead

University of Pennsylvania

OTHER

NCT04695392 - Restore Resilience in Critically Ill Children | Biotech Hunter | Biotech Hunter