HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study

CompletedOBSERVATIONAL
Enrollment

7,500

Participants

Timeline

Start Date

November 12, 2020

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Papillomavirus InfectionsUterine Cervical NeoplasmsSexual Transmitted Disease
Interventions
DIAGNOSTIC_TEST

16S rRNA gene sequencing of cervical secretions

"1. 16S rRNA gene sequencing of vaginal secretions: using NGS technology to assess the microbiota of the vaginal secretions~2. Microecology assessment of vaginal secretions: morphology test, functional assessment and Nugent score assessment of the vaginal secretions are included.~3. Genotyping of HPV and detection of sexually transmitted diseases pathogens based on the cervical exfoliated cells~4. Thinprep cytologic test of cervical exfoliated cells: to evaluate the grade of cervical intraepithelial neoplasia"

Trial Locations (42)

510000

Zhujiang Hospital, Guangzhou

Unknown

The First Affiliated Hospital of USTC, Hefei

The First Hospital of Lanzhou University, Lanzhou

Chaozhou Central Hospital, Chaozhou

Dongguan People's Hospital, Dongguan

Guangdong Provincial Hospital of Intergrated Traditional Chinese and Western Medicine, Foshan

Nanfang Hospital, Guangzhou

Taihe Branch of Nanfang Hospital, Guangzhou

The First Affiliated Hospital of Jinan University, Guangzhou

The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou

The Third Affiliated Hospital of Southern Medical University, Guangzhou

Huizhou Municipal Central Hospital, Huizhou

Peking University Shenzhen Hospital, Shenzhen

Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen

Shenzhen Luohu Hospital Group Luohu People's Hospital, Shenzhen

The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen

The Third People's Hospital of Shenzhen, Shenzhen

Xiaolan People's Hospital of Zhongshan, Zhongshan

The First Affiliated Hospital, Sun Yat-Sen Univeristy, Guangzhou

Zhuhai Women and Children's Hospital, Zhuhai

The Affiliated Hospital of Guizhou Medical University, Guiyang

The First People's Hospital of Zunyi, Zunyi

Yue Bei People's Hospital, Shaoguan

Hainan General Hospital, Haikou

The Second Hospital of Hebei Medical University, Shijiazhuang

The First Hospital fo Qiqihar, Qiqihar

The Second People's Hospital of Lianyungang, Lianyungang

Jilin Central General Hospital, Jilin

General Hospital of Ningxia Medical University, Yinchuan

Qinghai Red Cross Hospital, Xining

Jinan Central Hospital, Jinan

Obstetrics&Gynecology Hospital of Fudan University, Shanghai

Changzhi People's Hospital, Changzhi

The First Affiliated Hospital of Xi'an Jiaotong University, Xi’an

The Affiliated Hospital of Southwest Medical University, Luzhou

Tibet Autonomous Region People's Hospital, Lhasa

Yan'an Hospital of Kunming City, Kunming

Sir Run Run Shaw Hospital, Hanzhou

Changsha Central Hospital, Changsha

The Third Affiliated Hospital of CQMU, Chongqing

The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou

Shanghai East Hospital Tongji University, Shanghai

All Listed Sponsors
collaborator

Peking University First Hospital

OTHER

collaborator

The Affiliated Hospital Of Guizhou Medical University

OTHER

collaborator

Hainan General Hospital

OTHER

collaborator

LanZhou University

OTHER

collaborator

Lianyungang Hospital Affiliated Bengbu Medical College

OTHER

collaborator

General Hospital of Ningxia Medical University

OTHER

collaborator

Jinan Central Hospital

OTHER

collaborator

Tibet Autonomous Region People's Hospital

OTHER

collaborator

The Affiliated Hospital Of Southwest Medical University

OTHER

collaborator

Anhui Provincial Hospital

OTHER_GOV

collaborator

The First People's Hospital of Zunyi

OTHER

collaborator

The Third Affiliated Hospital of Southern Medical University

OTHER_GOV

collaborator

First Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Zhuhai Center for Maternal and Child Health Care

OTHER

collaborator

First Affiliated Hospital of Guangxi Medical University

OTHER

collaborator

Qinghai Red Cross Hospital

OTHER

collaborator

Changzhi People's Hospital

OTHER

collaborator

Shanghai East Hospital

OTHER

collaborator

Fifth Affiliated Hospital of Guangzhou Medical University

OTHER

collaborator

Huizhou Municipal Central Hospital

OTHER

collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

Yuebei People's Hospital

OTHER

collaborator

The Seventh Affiliated Hospital of Sun Yat-sen University

OTHER

collaborator

Fujian Maternity and Child Health Hospital

OTHER

collaborator

The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine

OTHER

collaborator

Henan Provincial People's Hospital

OTHER

collaborator

The Fifth Affiliated Hospital of Southern Medical University

OTHER

collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

First Hospital of China Medical University

OTHER

collaborator

Gansu Provincial Hospital

OTHER

lead

Zhujiang Hospital

OTHER

NCT04694495 - HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study | Biotech Hunter | Biotech Hunter