Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory

NACompletedINTERVENTIONAL
Enrollment

43

Participants

Timeline

Start Date

July 9, 2021

Primary Completion Date

February 24, 2023

Study Completion Date

February 24, 2023

Conditions
Normal Physiology
Interventions
DEVICE

TMS

The intervention of interest will be TMS delivered to the region of the left posterior parietal cortex with the greatest connectivity with the left hippocampus derived from the baseline resting-state fMRI session. This region was chosen because of its dense connections with the hippocampus, allowing stimulation of this location to modulate function of the hippocampal-cortical network. The control intervention target will be vertex, a commonly used active control site which does not influence neural or behavioral activity.

Trial Locations (1)

20892

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Neurological Disorders and Stroke (NINDS)

NIH