108
Participants
Start Date
December 15, 2020
Primary Completion Date
September 30, 2022
Study Completion Date
June 30, 2023
Etrasimod
Participants will receive etrasimod tablet by mouth, once daily during the 24-week Double-Blind and 28-week Extension Treatment Periods.
Placebo
Participants will receive etrasimod matching placebo tablet by mouth, once daily during the 24-week Double-Blind Treatment Period.
Etrasimod
Participants will receive etrasimod tablet by mouth, once daily during the 28-week Extension Treatment Period.
Footscray Hospital, Footscray
Vision Eye Institute, Melbourne
The Northern Hospital, Epping
MCES Practice Pty Ltd operating as Comprehensive Eye Surgeons (OCT Facility), Bellfield
Retina Specialists Victoria (OCT Facility), Camberwell
Eastern Clinical Research Unit, Box Hill
Eastern Health, Box Hill
Box Hill Eye Surgeons (OCT Facility), Box Hill North
Mater Misericordiae Ltd, Brisbane South
Buderim Eye Centre (OCT Facility), Buderim
Coastal Digestive Health, Maroochydore
Sunshine University Private Hospital, Birtinya
Queensland Respiratory Services ,Pulse Oceanside Medical{PFT Facility ), Birtinya
Dr Shiran DeSilva Respiratory Clinic, Mackay
Mackay Discount Drug Store, Mackay
Mater Misericordiae Hospital, Mackay
Queensland X-Ray, Mackay
Vision Eye Institute Mackay, Mackay
Coral Sea Clinical Research Institute, North Mackay
Modbury Hospital (OCT Facility), Modbury
Elizabeth Specialist Suites (PFT Facility), Elizabeth Vale
Lyell McEwin Hospital., Elizabeth Vale
Lyell McEwin Hospital, Elizabeth Vale
Centre Hospitalier Wallonie Picarde (CHWAPI), Tournai
University Hospital Zurich, Zurich
AZ St Lucas Brugge, Bruges
AZ Delta, Roeselare
Precision for Medicine GmbH, Berlin
West Shore Endoscopy Center, Camp Hill
Penn State Health Medical Group - Lemoyne (PFT only), Lemoyne
Medical Arts Allergy,PC (PFT Only), Harrisburg
Farrel Opthalmology(OCT only), Harrisburg
Susquehanna Research Group, LLC, Harrisburg
Harrisburg Eye Associates (OCT only), Harrisburg
Investigational Drug Services, Philadelphia
University of Pennsylvania, Philadelphia
Berks Center for Digestive Health, Wyomissing
"Berks Schuylkill Respiratory Specialists PFT Procedure Only", Wyomissing
"Eye Consultants of Pennsylvania, PC OCT Procedure Only", Wyomissing
Regional Gastroenterology Associates of Lancaster, Ltd., Wyomissing
Tower Health Reading Hospital, West Reading
Chesapeake Pulmonary and Critical Care Medicine (PFT Only), Chesapeake
Gastroenterology Associates of Tidewater - Endoscopy Center, Chesapeake
Gastroenterology Associates of Tidewater, Chesapeake
Wagner Macula and Retina Center (OCT only), Norfolk
Sleep Specialists of Tidewater - Virginia Beach (PFT Only), Virginia Beach
Wagner Macula and Retina Center (OCT only), Norfolk
Lynchburg Pulmonary Associates, Inc. (PFT only), Lynchburg
Blue Ridge Medical Research, Lynchburg
Harman Eye Center (OCT only), Forest
UNC Gastroenterology at Hillsborough, Hillsborough
lnvestigational Drug Services, University of North Carolina Hospitals (IP storage address), Chapel Hill
UNC Clinical Research Eastowne, Chapel Hill
UNC Hospitals Pulmonary Function Lab (PFT and DLCO procedures only), Chapel Hill
University of North Carolina - Memorial Hospital, Chapel Hill
UNC Endoscopy Center at Meadowmont, Chapel Hill
UNC Hospitals Pulmonary Specialty Clinic (PFT and DLCO procedures only), Chapel Hill
UNC Kittner Eye Center (OCT procedure only), Chapel Hill
Brier Creek Medical Pavilion, Raleigh
Duke Medical Plaza North Duke Street, Durham
Duke Eye Center, Durham
Duke University Medical Center, Durham
Investigational Drug Services (Pharmacy), Durham
Hospital Universitario de La Princesa, Madrid
Coastal Research Institute, Fayetteville
Cumberland Research Associates, LLC, Fayetteville
Georgia Eye Partners, Decatur
Atlanta Center for Gastroenterology, P.C., Decatur
Atlanta Endoscopy Center LTD, Decatur
Pulmonary & Sleep Specialist, Decatur
Digestive Healthcare of Georgia, Atlanta
Peachtree Allergy and Asthma Clinica - Pulmonary Function Test, Atlanta
Piedmont Hospital- DLCO, Atlanta
Ross Eyecare - Opthalmoscopy and OCT, Atlanta
Advanced Eye Center, Hialeah
Beraja Medical Institute (OCT), Coral Gables
The Endoscopy Center (Endoscopy Procedure), Miami
Research Associates of South Florida, Miami
Research Associates of South Florida, Miami
Juan Barrio, MD (PFT when needed), Miami
Jupiter Outpatient Surgery Center, Jupiter
RecioMed Clinical Research Network, Inc, Boynton Beach
Florida Eye Specialists and Cataract Institute, Riverview
Ambulatory Surgery Center, Tampa
Pulmonology & Sleep Disorders, Tampa
Bay Area Chest Physicians, P.A., - Pulmonary Function Test, Clearwater
West Coast Endoscopy Center, Clearwater
West Coast Endoscopy, Clearwater
MACULA CENTER Dana M. Deupree, M.D., F.A.C.S (OCT), Clearwater
Northwood Vision Optical Coherence Tomography (OCT), Clearwater
Safety Harbor Surgery Center, Clearwater
Gastro Florida (Regulatory & Administrative Duties), Clearwater
Central Florida Sleep Diagnostic & Treatment Center, Lakeland
Auzmer Research, Lakeland
Dr. Dennis Bassetti, MD, Sebring
Highlands Eye Institute, P.A., Sebring
The Surgery and Endoscopy Center, Sebring
Day Surgery Center, Winter Haven
Steelgate, Bradenton
Bayfront Health Seven Rivers (Liver Biopsy Location), Crystal River
Citrus Surgery and Endoscopy Center (EGD Location), Crystal River
Nature Coast Clinical Research, Inverness
West Coast Eye Institute (OCT Procedure Only), Inverness
Suncoast Endoscopy Center (EGD Location), Inverness
West Coast Eye Institute (OCT Procedure Only), Lecanto
Clinical Research Center of Alabama, LLC, Birmingham
Alabama Eye MD, Vestavia Hills
GastroHealth - St. Vincent's East, Birmingham
Madison Surgery Center, Madison
Avant Research Associates, LLC, Huntsville
Crestwood Medical Center, Huntsville
Baily Cove Eye Care, Huntsville
Digestive Health Specialists, Dothan
Dothan Eyecare - Dr. Brent McKinley (OCT Procedure Only), Dothan
Dothan Surgery Center (Colonoscopy Location), Dothan
Pulmonary Associates (PFT Procedure Only, Second Location ), Dothan
Flowers Hospital (PFT Procedure Only), Dothan
Vanderbilt GI Endoscopy Lab at One Hundred Oaks, Nashville
Vanderbilt Eye Institute, Nashville
Vanderbilt Pulmonary Medicine, Nashville
Vanderbilt University Medical Center - Digestive Disease Center, Nashville
Vanderbilt University Medical Center - Heart Station, Nashville
Franklin Woods Community Hospital (PFT Only), Johnson City
Pulmonary Associates of ET/Jeff Farrow, MD - PFT only, Johnson City
The Regional Eye Center - OCT only, Kingsport
Tri-Cities Gastroenterology, Kingsport
Ohio Gastroenterology Group, Dublin
Erdey Searcy Eye Group, Columbus
Geauga Sleep Center (PFT Only), Chardon
Great Lakes Medical Research, LLC, Mentor
The Endoscopy Center of Lake County, Mentor
Vitreo Retinal Consultants (OCT only), Painesville
Lake Pulmonary Associates (PFT only), Willoughby
Retina Specialists of Ohio(OCT only), Willoughby Hills
Leon A. Reid, III, M.D. (OCT), Cincinnati
Cincinnati Eye Institute (ophthalmic and OCT exams), Cincinnati
Consultants for Clinical Research, Cincinnati
Gastro Health Research, Cincinnati
Ohio GI and Liver Institute, Cincinnati
Tristate Endoscopy Center (Endoscopy), Cincinnati
UC Health Hoxworth (ophthalmic and OCT only), Cincinnati
UC Health Physicians Office Clifton (where subjects seen), Cincinnati
UC Health Pulmonary (PFT Location), Cincinnati
University of Cincinnati Medical Center Diagnostic Center (Endoscopy location), Cincinnati
UC Health Pulmonary (Pulmonary Function Testing), Cincinnati
Leon A. Reid, III, M.D. (OCT), Cincinnati
New Horizons Clinical Research (PFT), Cincinnati
University Endoscopy Center (Endoscopy location), Cincinnati
UC Health/Division of Digestive Diseases (where subjects seen), Cincinnati
Clark Memorial Health (PFTs), Jeffersonville
One Anesthesia, AACC Division, Jeffersonville
Baptist Health Floyd (PFTs), New Albany
Gastroenterology Health Partners, PLLC, (IP), New Albany
John Kenyon Eye Center (OCT), New Albany
One Anesthesia, PLLC, New Albany
Physicians Medical Center (Endoscopies), New Albany
Hospital Universitario Miguel Servet, Zaragoza
M Health Fairview Clinics and Surgery Center, Minneapolis
M Health Fairview University of Minnesota Medical Center, Minneapolis
University of Minnesota Health Clinical research unit, Minneapolis
University of Minnesota Health Opthalmology Clinic, Minneapolis
Mayo Clinic, Rochester
Rapid City Medical Center, LLP, Rapid City
Glen Endoscopy Center (Endoscopy Facility), Glenview
GI Alliance (PFT), Gurnee
Illinois Gastroenterology Group-Gurnee (Patients Seen; IP Delivered), Gurnee
Medical Eye Services LTD (Ophthalmoscopy with OCT), Gurnee
North Shore Endoscopy Center (Endoscopy), Lake Bluff
Libertyville Imaging Center (Diagnostic Imaging), Libertyville
Northwestern University Feinberg School of Medicine, Chicago
Quest, Lenexa
Cotton O'Neil Clinic (OCT Procedure Only), Topeka
Cotton O'Neil Clinic (PFT Procedure Only), Topeka
Cotton O'Neil Clinical Research Center, Digestive Health, Topeka
Celerion, Inc., Lincoln
Acadiana Endoscopy Center, Inc, Lafayette
Acadiana Gastroenterology Associates, Lafayette
Combined Gastro Research, LLC, Lafayette
Gastroenterology Clinic of Acadiana (IP address), Lafayette
Lafayette General Endoscopy Center, Lafayette
Lafayette Family Eye Care, Lafayette
Little Rock Eye Clinic, Little Rock
Four Seasons Allergy and Asthma, Little Rock
Applied Research Center of Arkansas, Little Rock
Premier Gastroenterology Endoscopy Center, Little Rock
Premier Gastroenterology, Little Rock
Norman Endoscopy Center, Norman
Digestive Disease Specialists, Inc. Endoscopy Lab, Oklahoma City
Digestive Disease Specialists, Inc., Oklahoma City
Pulmonary Physicians of Oklahoma, Oklahoma City
Retinal Center of Oklahoma, Oklahoma City
Central Sooner Research, Oklahoma City
Johnston Eye, Oklahoma City
The Eye Place Jenny Fan, OD (OCT Only), Plano
Pulmonary Medicine Consultants (PFT with DCLO only), Richardson
Digestive Health Center (Endoscopy), Dallas
Precision for Medicine, Houston
Bay Area Houston Endoscopy Center (Endoscopy), Webster
Coastal Eye Associates (OCT), Webster
GI Alliance (Patients Seen), Webster
Houston Lung and Sleep Clinic, PA (PFT), Webster
CHRJSTUS Santa Rosa Physicians Ambulatory Surgery Center-new Braunfels(Endoscopy), New Braunfels
Tyrus Schroeder (PFT), New Braunfels
Advanced Imaging, San Marcos
Central Texas Eye Center (OCT), San Marcos
CHRJSTUS Santa Rosa Physicians Ambulatory Surgery Center - San Marcos (Endoscopy), San Marcos
Grand Teton Research Group, PLLC, Idaho Falls
Grand Teton Surgical Center, Idaho Falls
Idaho Falls Pulmonary/ Sleep and Critical Care Specialists (PFT procedure only), Idaho Falls
Premier Eye Care of Eastern Idaho (OCT procedure only), Idaho Falls
University of Utah Gastroenterology Division Research, Salt Lake City
Huntsman Cancer Hospital, Salt Lake City
University of Utah Hospital, Salt Lake City
University Of Utah School Of Medicine, Salt Lake City
Arizona Digestive Health - Sun City, Sun City
Sun City Endoscopy Center (Endoscopy), Sun City
Arizona Retina Institute/ Phoenix Retina Associates(OCT), Peoria
SimonMed Imaging (Imaging), Peoria
Clinical Trials Unit, Los Angeles
Keck Hospital of USC, Los Angeles
USC IDS Pharmacy, Los Angeles
Advanced Vision Care (OCT), Los Angeles
Inland Pulmonary Specialists [PFT Only], Lake Elsinore
United Surgery Center Murrieta [Endoscopy Only], Murrieta
United Medical Doctors, Murrieta
California Eye Professionals [OCT Only], Temecula
United Surgery Center Temecula [Endoscopy Only], Temecula
Isight Vision Care, Fountain Valley
Mile Square Surgery Center, Fountain Valley
Pulmonary & Sleep Consultants, Fountain Valley
Paragon Rx Clinical, Inc., Garden Grove
Advanced Endoscopy and Pain Center - EGD & Biopsy Collection, Lancaster
Advanced Endoscopy and Pain Center, Lancaster
Antelope Valley Eye Care - OCT, Lancaster
Antelope Valley Eye Care, Lancaster
Antelope Valley Lung and Sleep Institute, Lancaster
Apollo Surgery Center, Lancaster
AV Pediatrics, Allergy and Family Medicine - PFT, Physical Exams, Lab Reviews, ECG Reviews, Lancaster
Gastro Care Institute, Lancaster
Jatinder S. Pruthi, MD FACG CPI - Physical Exams, Lab Reviews, ECG Reviews, Lancaster
Om Research LLC, Lancaster
Del Negro & Senft Eye Associates, Brick
Allied Health Clinical Research Organization, LLC (IP Address), Brick
Seashore Surgical Institute, Brick
Shore Pulmonary, PA, Brick
Allied Health Clinical Research Organization, LLC, Freehold
Del Negro & Senft Eye associates, Neptune City
Del Negro & Senft eye Associates, Red Bank
Clinical and Translational Research Center Outpatient Unit, Chapel Hill
Vanderbilt University Medical Center - GI Research Office, Nashville
Vanderbilt University Medical Center GI Endoscopy Lab, Nashville
Mount Sinai Services Inc. Dr George Charames, Toronto
Amsterdam UMC, location AMC, Amsterdam
Hospital General Universitario de Alicante, Alicante
Universitätsspital Zürich, Zurich
Universtätsspital Zürich, Zurich
Lead Sponsor
Arena is a wholly owned subsidiary of Pfizer
INDUSTRY
Pfizer
INDUSTRY