Propranolol With Standard Chemoradiation for Esophageal Adenocarcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

106

Participants

Timeline

Start Date

April 1, 2021

Primary Completion Date

April 1, 2027

Study Completion Date

April 1, 2027

Conditions
Esophageal Adenocarcinoma
Interventions
DRUG

Carboplatin

Given IV

RADIATION

3 Dimensional Conformal Radiation Therapy

Undergo 3D CRT

DRUG

Propranolol

Subject will be treated with 30 mg po BID Propranolol for up to 6 weeks

RADIATION

Intensity Modulated Radiation Therapy

Undergo IMRT

DRUG

Paclitaxel

Given IV

Trial Locations (1)

14263

RECRUITING

Roswell Park Cancer Institute, Buffalo

All Listed Sponsors
lead

Roswell Park Cancer Institute

OTHER