Ketogenic Dietary Interventions in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

NACompletedINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

January 10, 2021

Primary Completion Date

August 12, 2022

Study Completion Date

August 12, 2022

Conditions
ADPKD
Interventions
OTHER

Ketogenic diet

Patients will follow a classical ketogenic diet for 3 months

OTHER

3-days water-fasting

Patients will perform water fasting on 3 consecutive days within the first 14 days of each of the 3 months. In one of the 3 months they are - if required - allowed to split the 3 days into periods of 1 and 2 days. On all other days of the intervention period they are allowed to eat ad libitum.

OTHER

Control

Patients are allowed to eat ad libitum, but will be advised that low salt intake (\< 5-7 g/day) and sufficient fluid intake (\>3 l/day) which is considered beneficial in ADPKD.

Trial Locations (1)

50937

Department II of Internal Medicine, University Hospital of Cologne, Cologne

All Listed Sponsors
lead

University of Cologne

OTHER

NCT04680780 - Ketogenic Dietary Interventions in Autosomal Dominant Polycystic Kidney Disease (ADPKD) | Biotech Hunter | Biotech Hunter