Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

PHASE2CompletedINTERVENTIONAL
Enrollment

310

Participants

Timeline

Start Date

December 7, 2020

Primary Completion Date

October 21, 2021

Study Completion Date

November 2, 2021

Conditions
Refractory Chronic Cough
Interventions
DRUG

BLU-5937

Oral administration of BLU-5937 Tablets

DRUG

Placebo

Oral administration of matching placebo for BLU-5937 Tablets

Trial Locations (116)

1036

Synexus Budapest - Magyarország Egészségügyi Szolgáltató Kft, Budapest

2660

Dr. Kenessey Albert Korhaz-Rendelointezet, Balassagyarmat

2800

Szent Borbála Kórház, Tatabánya

5700

Synexus Gyula - Magyarország Egészségügyi Szolgáltató Kft, Gyula

7635

Da Vinci Maganklinika, Pécs

8900

Synexus Zalaegerszeg Magyarország Egészségügyi Kft, Zalaegerszeg

10455

CHEAR Center LLC, The Bronx

10969

Ärztezentrum Axel Springer Passage, Berlin

16601

Clinical Research Associates Of Central Pa, Altoona

19055

Kfns Klinische Forschung Schwerin, Schwerin

21237

Little Rock Allergy and Asthma Clinical Research Center, Little Rock

23188

TPMG Lung & Sleep Specialist, Williamsburg

27103

Southeastern Research Center, Winston-Salem

28054

Clinical Research of Gastonia, Gastonia

28277

American Health Research Inc, Charlotte

29420

National Allergy and Asthma Research, Charleston

29621

Synexus Clinical Research US, Inc., Anderson

29732

Clinical Research of Rock Hill, Rock Hill

30046

IACT Health - Lawrenceville, Lawrenceville

31326

IACT Health - Rincon, Rincon

31904

IACT Health - Columbus, Columbus

32803

Central Florida Pulmonary Group PA, Orlando

33014

ProCare Clinical Research, Miami Lakes

33016

Floridian Clinical Research, Hialeah

Sweet Hope Research Specialty, Inc., Hialeah

33172

Lenus Research & Medical Group, Sweetwater

33701

Plicní ambulance Rokycany s.r.o., Rokycany

33765

St. Francis Medical Institute, Clearwater

33778

Sher Allergy Specialist/Center for Cough, Largo

34748

Medical Research of Central Florida, Leesburg

35037

Zentrum für ambulante pneumologische Forschung Marburg GbR, Marburg

37067

Clinical Trials Center of Middle Tennessee, Franklin

41017

Abraham Research PLLC, Fort Mitchell

43215

Remington Davis Inc, Columbus

44195

The Cleveland Clinic Foundation, Cleveland

45231

Bernstein Clinical Research Center Inc, Cincinnati

47714

AES - Synexus Clinical Research US, Inc. - Evansville, Evansville

53127

Universitätsklinikum Bonn, Bonn

55125

Minnesota Lung Center, Woodbury

55435

Minnesota Lung Center, Edina

55905

Mayo Clinic, Rochester

59808

Montana Medical Research, Missoula

60313

Synexus Frankfurt Research Centre, Frankfurt am Main

60596

IKF Pneumologie, Frankfurt am Main

61761

Sneeze Wheeze and Itch Associates LLC, Normal

63017

The Lung Research Center, LLC, Chesterfield

63141

The Clinical Research Center LLC, St Louis

63263

Ballenberger. Freytag. Wenisch - Institut fuer klinische Forschung GmbH, Neu-Isenburg

65201

University of Missouri, ENT and Allergy Center of Missouri, Columbia

68124

Creighton University Medical Center, Omaha

69126

Thoraxklinik-Heidelberg gGmbH, Heidelberg

74136

Vital Prospects Clinical Research Institute PC, Tulsa

75069

Metroplex Pulmonary and Sleep Medicine Center, McKinney

75092

Sherman Clinical Research, Sherman

75231

Pharmaceutical Research & Consulting Inc, Dallas

76712

Allergy Asthma Research Institute, Waco

77084

Village Research, LLC, Houston

78229

Diagnostics Research Group, San Antonio

79902

El Paso Pulmonary Association, El Paso

80230

Colorado Allergy and Asthma Centers, Denver

84020

Intermountain Clinical Research, Draper

85381

Phoenix Medical Research Inc, Peoria

87102

Albuquerque Clinical Trials Inc, Albuquerque

90048

Southern California Institute For Respiratory Diseases, Inc, Los Angeles

91324

California Medical Research Associates, Inc., Northridge

92120

Allergy Associates Medical Group Inc., San Diego

92691

Allergy and Asthma Associates of Southern California, Mission Viejo

95117

Allergy and Asthma Associates of Santa Clara Valley Research Center, San Jose

02747

Infinity Medical Research Inc, North Dartmouth

07901

Atlantic Respiratory Institute, Summit

L8N 3Z5

McMaster University Medical Centre, Hamilton

G1N 4V3

Diex Recherche - Québec, Québec

G1V 4W2

Clinique Spécialisée en Allergie de la Capitale, Québec

M5T 3A9

Inspiration Research Limited, Toronto

G8T 7A1

C I C Maurice Inc, Trois-Rivières

G6P 6P6

Diex Recherche - Victoriaville, Victoriaville

250 01

MUDr. I. Cierná Peterová s.r.o., Brandýs nad Labem-Stará Boleslav

473 01

Pneumologie Varnsdorf S.r.o., Nový Bor

120 00

Synexus Czech s.r.o., Prague

377 01

MediTrial s.r.o., Jindřichův Hradec

386 01

MUDr. Jaroslav Mares - odborny lekar pro obor tuberkulosa a respiracni nemoci, Strakonice

415 01

Plicni stredisko Teplice s.r.o., Teplice

01069

Klinische Forschung Dresden GmbH (KFGN), Dresden

04103

Synexus Leipzig Research Centre, Leipzig

31-826

Osrodek Badan Klinicznych CLINSANTE S.C. Ewa Galczak-Nowak Malgorzata Trzaska, Bydgoszcz

85-231

Medical Center Kermed, Bydgoszcz

85-796

Centrum Medyczne Bydgoszcz - PRATIA, Bydgoszcz

33-100

Alergo-Med Specjalistyczna Przychodnia Lekarska Sp. z.o.o, Tarnów

23-100

KLIMED, Bychawa

20-078

Clinical Best Solutions -Lublin, Lublin

20-552

Centrum Alergologii Specjalistyczna Przychodnia Alergologiczna, Lublin

01-869

Centrum Medyczne Warszawa - PRATIA, Warsaw

15-010

Prywatny Gabinet Internistyczno-Alergologiczny, Bialystok

80-382

Synexus Polska Sp. z o.o. Oddzial w Gdansku, Gdansk

42-202

Synexus Polska Sp. z o.o. Oddzial w Czestochowie, Częstochowa

31-572

Centrum Medyczne Wos i Piwowarczyk, Kraków

90-127

Synexus Polska Sp. Z o.o Oddzial w Lodzi, Lodz

27-400

Ostrowieckie Centrum Medyczne Spólka Cywilna Anna Olech-Cudzik, Krzysztof Cudzik, Ostrowiec Świętokrzyski

B15 2SQ

Synexus Midlands Clinical Research Centre, Birmingham

BS37 4AX

West Walk Surgery, Bristol

NN18 9EZ

MeDiNova Northamptonshire Quality Research Site, Corby

HU16 5JQ

Castle Hill Hospital, Cottingham

CV8 1JD

MeDiNova Warwickshire Quality Research Site, Kenilworth

SE5 9RS

Kings College Hospital, London

SW3 6NP

Royal Brompton Hospital, London

M15 6SX

NW Consortium Manchester, Manchester

M23 9LT

Wythenshawe Hospital - PPDS, Manchester

HA6 2RN

MeDiNova North London Quality Research Site, Middlesex

NE29 8NH

North Tyneside General Hospital, North Shields

RM1 3PJ

MeDiNova East London Quality Research Site, Romford

BD18 3SA

MeDiNova Yorkshire Quality Research Site, Shipley

DA14 6LT

MeDiNova South London Quality Research Site, Sidcup

RG40 1XS

MeDiNova West London Quality Research Site, Wokingham

BT7 2EB

Ormeau Clinical Trials Limited, Belfast

BT9 7AB

Belfast City Hospital, Belfast

G20 0SP

AES - Synexus Scotland Clinical Research Centre, Glasgow

All Listed Sponsors
lead

Bellus Health Inc. - a GSK company

INDUSTRY

NCT04678206 - Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough | Biotech Hunter | Biotech Hunter