Relationship Between Oral DMT Burden and Adherence in MS

Enrolling by invitationOBSERVATIONAL
Enrollment

323

Participants

Timeline

Start Date

September 25, 2020

Primary Completion Date

November 19, 2025

Study Completion Date

July 11, 2026

Conditions
Multiple SclerosisAdherence, Medication
Interventions
DRUG

Cladribine

Cladribine is a purine antimetabolite indicated for the treatment of relapsing forms of multiple sclerosis, to include relapsing-remitting disease and active secondary progressive disease, in adults.

DRUG

Dimethyl fumarate

Dimethyl fumarate is indicated for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults

DRUG

Fingolimod

Fingolimod is a sphingosine 1-phosphate receptor modulator indicated for the treatment of patients with relapsing forms of multiple sclerosis to reduce the frequency of clinical exacerbations and to delay the accumulation of physical disability.

DRUG

Teriflunomide

Teriflunomide is a pyrimidine synthesis inhibitor indicated for the treatment of patients with relapsing forms of multiple sclerosis.

DRUG

Ozanimod

Ozanimod is a sphingosine-1-phosphate receptor modulator indicated for the treatment of patients with relapsing forms of multiple sclerosis.

DRUG

Diroximel fumarate

Diroximel fumarate is indicated for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Trial Locations (1)

3800

Monash University, Melbourne

All Listed Sponsors
lead

Monash University

OTHER