Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease

Using the RC+S pulse generator, patients receive clinically-optimized open loop DBS stimulation to the pallidum.

Using the RC+S pulse generator, the patients will receive closed-loop stimulation at random time points. These random stimulation times will in total equal the total amount of time of active movement.

Using the RC+S pulse generator, the patients will receive closed-loop stimulation during time of contralateral limb movement (e.g. left brain stimulation during right leg/arm movement).

Using the RC+S pulse generator, the patients will receive closed-loop stimulation during time of no movement for the contralateral limb (e.g. left brain stimulation while right leg/arm is not moving).