NCT04675151 - Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia | Biotech Hunter

Enrollment

150

Participants

Timeline

Start Date

February 15, 2021

Primary Completion Date

May 17, 2021

Study Completion Date

June 30, 2021

Conditions

Presbyopia

Interventions

DRUG

Phentolamine Ophthalmic Solution 0.75%

0.75% phentolamine ophthalmic solution (Nyxol), a non-selective alpha-1 and alpha-2 adrenergic antagonist

DRUG

Pilocarpine

Pilocarpine ophthalmic solution

OTHER

Placebo

Topical sterile ophthalmic solution

Trial Locations (17)

12603

Clinical Site 16, Poughkeepsie

30041

Clinical Site 10, Roswell

32751

Clinical Site 11, Maitland

32779

Clinical Site 5, Longwood

34239

Clinical Site 8, Sarasota

34461

Clinical Site 13, Crystal River

38119

Clinical Site 1, Memphis

43065

Clinical Site 15, Powell

44115

Clinical Site 7, Cleveland

45242

Clinical Site 9, Cincinnati

45701

Clinical Site 2, Athens

58103

Clinical Site 14, Fargo

63101

Clinical Site 18, St Louis

66762

Clinical Site 3, Pittsburg

92653

Clinical Site 12, Laguna Hills

92663

Clinical Site 6, Newport Beach

02888

Clinical Site 4, Warwick