Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients

NACompletedINTERVENTIONAL
Enrollment

92

Participants

Timeline

Start Date

December 10, 2020

Primary Completion Date

March 10, 2021

Study Completion Date

March 10, 2021

Conditions
Anesthesia, SpinalElderly
Interventions
DRUG

Bupivacaine-fentanyl

"Bupivacaine-Fentanyl (BF) group (46 patients): will receive spinal anaesthesia with 12.5 mg hyperbaric Bupivacaine 0.5% (2.5 mL) plus 25 µg Fentanyl (0.5 mL) and (0.5 mL) normal saline added in the same syringe in a total volume of 3.5 mL.~Bupivacaine-Fentanyl-Naloxone (BFN) group (46 patients): will receive spinal anaesthesia with 12.5 mg hyperbaric Bupivacaine 0.5% (2.5 mL) plus 25 µg Fentanyl (0.5 mL) and 20 µg Naloxone (prepared in 0.5 mL normal saline) added in the same syringe in a total volume of 3.5 mL."

Trial Locations (1)

Unknown

Kasralainy, Cairo

All Listed Sponsors
collaborator

Mansoura University

OTHER

lead

Kasr El Aini Hospital

OTHER

NCT04673812 - Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients | Biotech Hunter | Biotech Hunter