Epi-on PiXL for the Treatment of Progressive Keratoconus.

NAActive, not recruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

March 20, 2019

Primary Completion Date

February 5, 2026

Study Completion Date

February 5, 2026

Conditions
KeratoconusCorneal CrosslinkingCorneal DensitometryScheimpflug PhotographyCorneal DisorderEye Diseases
Interventions
PROCEDURE

Epi-on PiXL in high oxygen

After local anaesthetics, the keratoconus cornea is soaked in Riboflavin by repeated topical application during 10 minutes. A Riboflavin soaked sponge is used to lightly disrupt the epithelium tight junctions, without epithelium debridement. The cornea is illuminated with PiXL under 16:40 minutes during continuously delivery of humidified high oxygen via specific oxygen googles. The UV-dosage is individually customized based upon Kmax; for \< 45 Diopters (D) 7.2J/cm\^2 will be used; for 45-50D 10J/cm\^2 will be used; for \> 50D 15 J/cm\^2 will be used.

Trial Locations (1)

90185

Umeå University Hospital, Umeå

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Glaukos Corporation

INDUSTRY

lead

Umeå University

OTHER