Nomogram to Predict Breast Cancer Related Lymphedema

NARecruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

December 11, 2020

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2027

Conditions
Breast CancerAxillary Lymph Node DissectionBreast Cancer Related LymphedemaAxillary Reverse Mapping
Interventions
PROCEDURE

Axillary surgery based on lymphedema prediction nomogram

Based on the intraoperative lymphedema prediction nomogram, individualized treatment was recommended to breast cancer patients with different level of risk. For patients with low possibility of developing breast cancer related lymphedema, it was not necessary to preserve arm lymphatics. While the breast cancer patients who were performed mastectomy and ALND with 28 kg/m2 prepared to receive taxane-based chemotherapy, supraclavicular and infraclavicular radiotherapy, according to the established intraoperative nomogram, the proportion of the arm lymph flow above the axillary vein needed to exceed 52%. Otherwise, the arm lymphatics should be identified and preserved.

Trial Locations (1)

430071

RECRUITING

Zhongnan Hospital of Wuhan University, Wuhan

All Listed Sponsors
lead

Wuhan University

OTHER