NCT04665037View on ClinicalTrials.gov

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 22, 2022

Primary Completion Date

December 16, 2026

Study Completion Date

December 31, 2026

Conditions
Invasive Fungal Infection
Interventions
DRUG

Posaconazole IV 6 mg/kg

POS 6 mg/kg body weight by IV infusion

DRUG

Posaconazole PFS 6 mg/kg

POS nominal 6 mg/kg body weight based on weight bands taken orally

Trial Locations (26)

1200

RECRUITING

UCL Saint Luc ( Site 1050), Brussels

3000

RECRUITING

UZ Leuven ( Site 1051), Leuven

9000

RECRUITING

UZ Gent ( Site 1052), Ghent

15038

RECRUITING

Instituto Nacional de Enfermedades Neoplasicas ( Site 1601), Lima

27710

COMPLETED

Duke University Medical Center ( Site 2106), Durham

33155

COMPLETED

Nicklaus Children's Hospital ( Site 2109), Miami

60611

RECRUITING

Ann & Robert H. Lurie Children's Hospital of Chicago ( Site 2104), Chicago

64460

RECRUITING

"Hospital Universitario Dr. Jose Eleuterio Gonzalez-Infectologia ( Site 2203)", Monterrey

76014

RECRUITING

Ivano-Frankivsk Regional Pediatric Clinical Hospital ( Site 1911), Ivano-Frankivsk

78411

COMPLETED

Driscoll Children's Hospital ( Site 2113), Corpus Christi

92123

COMPLETED

Rady Children's Hospital-San Diego ( Site 2101), San Diego

194291

COMPLETED

Mechnikov State Medical University ( Site 1803), Saint Petersburg

197022

COMPLETED

Pavlov State Medical University ( Site 1801), Saint Petersburg

620149

COMPLETED

Regional Children Clinical Hospital 1 ( Site 1802), Yekaterinburg

3109601

RECRUITING

Rambam Medical Center ( Site 1402), Haifa

5265601

RECRUITING

Sheba Medical Center ( Site 1404), Ramat Gan

6423906

RECRUITING

Sourasky Medical Center ( Site 1403), Tel Aviv

9112001

COMPLETED

Hadassah Ein Karem Hebrew University Medical Center ( Site 1401), Jerusalem

115 27

COMPLETED

Athens Childrens Hospital Aglaia Kyriakou ( Site 1102), Athens

546 42

RECRUITING

"General Hospital of Thessaloniki Ippokrateio ( Site 1100)", Thessaloniki

04530

RECRUITING

Instituto Nacional de Pediatria-Unidad de Apoyo a la Investigación Clínica ( Site 2200), Mexico City

06720

RECRUITING

Hospital Infantil de Mexico Federico Gomez-Infectious Diseases ( Site 2202), Mexico City

50-556

RECRUITING

Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckieg-Klinika Transplantacji Szpiku, Onkolog ( Site 1708), Wroclaw

10-561

COMPLETED

Wojewodzki Specjalistyczny Szpital Dzieciecy ( Site 1705), Olsztyn

03080

RECRUITING

Seoul National University Hospital-Pediatrics ( Site 2600), Seoul

01135

RECRUITING

"NATIONAL CHILDREN'S SPECIALIZED HOSPITAL OKHMATDYT OF THE -Intensive Care Unit ( Site 1912)", Kiev

All Listed Sponsors
lead

Merck Sharp & Dohme LLC

INDUSTRY