210
Participants
Start Date
April 16, 2021
Primary Completion Date
December 31, 2028
Study Completion Date
December 31, 2028
Pars plana vitrectomy
Pars plana vitrectomy
Intravitreal 2 mg aflibercept (Eylea, Bayer) will be injected at baseline then monthly for two further doses, then 2-monthly until month 12
Intravitreal 2 mg aflibercept (Eylea, Bayer) will be injected at baseline then monthly for two further doses, then 2-monthly until month 12.
subretinal injection of recombinant TPA (Alteplase) up to a maximum of 25 micrograms in 0.2 mls
Subretinal injection of recombinant TPA (Alteplase, Actilyse, Boehringer Ingelheim) up to a maximum of 25 micrograms in 0.2 mls.
Intravitreal 20% sulfahexafluoride (SF6) gas tamponade
Intravitreal 20% sulfahexafluoride (SF6) gas tamponade.
RECRUITING
University Medical Center Hamburg Eppendorf, Hamburg
RECRUITING
Ludwig Maximilians-University München, München
RECRUITING
Augenzentrum am St. Franziskus-Hospital Münster, Münster
RECRUITING
Ulm University Hospital, Ulm
RECRUITING
University hospital of Würzburg, Würzburg
WITHDRAWN
University Hospitals Sussex NHS Trust, Brighton
RECRUITING
Royal Devon and Exeter Hospital, Exeter
RECRUITING
Gartnavel General Hospital, Glasgow
RECRUITING
Leicester Royal Infirmary, Leicester
RECRUITING
Manchester Royal Eye Hospital, Manchester
RECRUITING
James Cook University Hospital, (South Tees NHSFT), Middlesbrough
RECRUITING
Nottingham University Hospitals, Nottingham
RECRUITING
University Hospitals Plymouth NHST, Plymouth
RECRUITING
New Cross Hosp, Royal Wolverhampton NHST, Wolverhampton
RECRUITING
Mid and South Essex NHS Foundation Trust, Chelmsford
RECRUITING
Kent & Canterbury Hospital (East Kent University), Canterbury
RECRUITING
King's College Hospital NHS Foundation Trust, London
RECRUITING
The Princess Alexandra Eye Pavilion, Edinburgh
RECRUITING
Sunderland Eye Infimary, Sunderland
RECRUITING
Hull Royal Infirmary, Hull
RECRUITING
Belfast Health and Social Care Trust, Belfast
RECRUITING
Bristol Eye Hospital, Bristol
RECRUITING
Royal Liverpool University Hospital, Liverpool
RECRUITING
Barts Health NHST trust - Whipps Cross University Hospital, London
RECRUITING
Moorfields Eye Hospital, London
RECRUITING
Imperial College Healthcare NHS Foundation Trust (The Western Eye Hospital), London
RECRUITING
Maidstone and Tunbridge Wells NHS Trust, Maidstone
RECRUITING
Royal Victoria Infirmary, Newcastle upon Tyne
RECRUITING
Oxford University Hospitals NHS Foundation Trust, Oxford
RECRUITING
University Hospital Southampton NHS foundation Trust, Southampton
RECRUITING
Torbay and South Devon NHS, Torquay
King's College London
OTHER
Fight for Sight (Funder)
UNKNOWN
King's College Hospital NHS Trust
OTHER